Anti-Phospho-HNRNPA0-Ser84 antibody (STJA0009954)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from human HNRPA0 (Phospho-Ser84)
General Information
| Short Description | Rabbit polyclonal anti-Phospho-Heterogeneous nuclear ribonucleoprotein A0-Ser84 for use in WB in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen. |
| Dilution Range | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | HNRNPA0 |
| Gene ID | 10949 |
| Uniprot ID | ROA0_HUMAN |
| Immunogen | Synthesized peptide derived from human HNRPA0 (Phospho-Ser84) |
| Specificity | This antibody detects endogenous levels of HNRPA0 (Phospho-Ser84) at Human, Mouse, Rat |
Additional Info
| Post Translational Modifications | Phosphorylated at Ser-84 by MAPKAPK2 in response to LPS treatment, promoting stabilization of GADD45A mRNA. Arg-291 is dimethylated, probably to asymmetric dimethylarginine. |
| Function | mRNA-binding component of ribonucleosomes. Specifically binds AU-rich element (ARE)-containing mRNAs. Involved in post-transcriptional regulation of cytokines mRNAs. |
| Protein Name | Heterogeneous Nuclear Ribonucleoprotein A0Hnrnp A0 |
| Database Links | |
| Cellular Localisation | NucleusComponent Of Ribonucleosomes |
| Alternative Antibody Names | Anti-Heterogeneous Nuclear Ribonucleoprotein A0 antibodyAnti-Hnrnp A0 antibodyAnti-HNRNPA0 antibodyAnti-HNRPA0 antibody |
Information sourced from Uniprot.org