Anti-Phospho-GAP43-S41 antibody (STJ13101134)
SPECIFICATIONS
ClonalityPolyclonal
HostSheep
ConjugationUnconjugated
IsotypeIgG
ImmunogenA synthetic peptide to phospho S41 of human GAP-43 conjugated to blue carrier protein was used as the antigen. The antigen is homologous in rat, mouse, zebra fish and chicken.
General Information
| Short Description | Sheep polyclonal anti-Phospho-GAP43-S41 for use in IHC in Human, Rat and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | IHC |
| Host | Sheep |
| Reactivity | Human/Rat/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Purification | IgG purified |
| Dilution Range | IHC. A concentration of 10-50 µg/ml is recommended. The optimal concentration should be determined by the end user. Not yet tested in other applications. This antibody may also recognise the unphosphorylated form. |
| Formulation | Lyophilised |
| Storage Instruction | Maintain the lyophilised/reconstituted antibodies frozen at-20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, Glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles. |
Target Information
| Gene Symbol | GAP43 |
| Gene ID | 2596 |
| Uniprot ID | NEUM_HUMAN |
| Immunogen | A synthetic peptide to phospho S41 of human GAP-43 conjugated to blue carrier protein was used as the antigen. The antigen is homologous in rat, mouse, zebra fish and chicken. |
| Specificity | Specific for GAP-43. |
Additional Info
| Function | This protein is associated with nerve growth. It is a major component of the motile 'growth cones' that form the tips of elongating axons. Plays a role in axonal and dendritic filopodia induction. |
| Protein Name | NeuromodulinAxonal Membrane Protein Gap-43Growth-Associated Protein 43Neural Phosphoprotein B-50Pp46 |
| Database Links | Reactome: R-HSA-373760 |
| Cellular Localisation | Cell MembranePeripheral Membrane ProteinCytoplasmic SideCell ProjectionGrowth Cone MembraneSynapseFilopodium MembranePerikaryonDendriteAxonCytoplasmCytoplasmic Surface Of Growth Cone And Synaptic Plasma Membranes |
| Alternative Antibody Names | Anti-Neuromodulin antibodyAnti-Axonal Membrane Protein Gap-43 antibodyAnti-Growth-Associated Protein 43 antibodyAnti-Neural Phosphoprotein B-50 antibodyAnti-Pp46 antibodyAnti-GAP43 antibody |
Information sourced from Uniprot.org