Anti-Phospho-GAB1-Tyr307 antibody (STJ91230)

SKU:
STJ91230

Current Stock:
Host: Rabbit
Applications: IHC/IF/ELISA
Reactivity: Human/Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-Phospho-GRB2-associated-binding protein 1-Tyr307 is suitable for use in Immunohistochemistry, Immunofluorescence and ELISA research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/mL
Dilution Range: IHC 1:100-1:300
ELISA 1:40000
IF 1:50-200
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: GAB1
Gene ID: 2549
Uniprot ID: GAB1_HUMAN
Specificity: Phospho-Gab 1 (Y307) Polyclonal Antibody detects endogenous levels of Gab 1 protein only when phosphorylated at Y307.
Immunogen: Synthesized phospho-peptide around the phosphorylation site of human Gab 1 (phospho Tyr307)
Function Adapter protein that plays a role in intracellular signaling cascades triggered by activated receptor-type kinases. Plays a role in FGFR1 signaling. Probably involved in signaling by the epidermal growth factor receptor (EGFR) and the insulin receptor (INSR). Involved in the MET/HGF-signaling pathway.
Protein Name Grb2-Associated-Binding Protein 1
Grb2-Associated Binder 1
Growth Factor Receptor Bound Protein 2-Associated Protein 1
Database Links Reactome: R-HSA-109704
Reactome: R-HSA-1236382
Reactome: R-HSA-1257604
Reactome: R-HSA-180292
Reactome: R-HSA-1963642
Reactome: R-HSA-2219530
Reactome: R-HSA-5637810
Reactome: R-HSA-5654689
Reactome: R-HSA-5654695
Reactome: R-HSA-5654710
Reactome: R-HSA-5654720
Reactome: R-HSA-5655253
Reactome: R-HSA-5655291
Reactome: R-HSA-5655302
Reactome: R-HSA-5655332
Reactome: R-HSA-6811558
Reactome: R-HSA-8851907
Reactome: R-HSA-8853659
Reactome: R-HSA-8865999
Reactome: R-HSA-8875555
Reactome: R-HSA-8875656
Reactome: R-HSA-9027276
Reactome: R-HSA-9028335
Reactome: R-HSA-9664565
Reactome: R-HSA-9665348
Alternative Antibody Names Anti-Grb2-Associated-Binding Protein 1 antibody
Anti-Grb2-Associated Binder 1 antibody
Anti-Growth Factor Receptor Bound Protein 2-Associated Protein 1 antibody
Anti-GAB1 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance