• Immunohistochemistry analysis of paraffin-embedded human breast carcinoma, using FADD (Phospho-Ser191) Antibody. The picture on the right is blocked with the phospho peptide.
  • Western blot analysis of lysates from Jurkat cells treated with PMA 125ng/ml 30', using FADD (Phospho-Ser191) Antibody. The lane on the right is blocked with the phospho peptide.
  • Western blot analysis of JK cells using Phospho-FADD (S191) Polyclonal Antibody

Anti-Phospho-FADD-Ser191 antibody (157-206 aa) (STJ90998)

SKU:
STJ90998

£46.00 - £226.00
Current Stock:
Host: Rabbit
Applications: WB/IHC/IF/ELISA
Reactivity: Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-Phospho-FADD-Ser191 (157-206 aa) is suitable for use in Western Blot, Immunohistochemistry, Immunofluorescence and ELISA research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/mL
Dilution Range: WB 1:500-1:2000
IHC 1:100-1:300
ELISA 1:5000
IF 1:50-200
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Immunogen Region: 157-206 aa
Specificity: Phospho-FADD (S191) Polyclonal Antibody detects endogenous levels of FADD protein only when phosphorylated at S191.
Immunogen: The antiserum was produced against synthesized peptide derived from mouse FADD around the phosphorylation site of Ser191 at the amino acid range 157-206
Function Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis. Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling.
Protein Name Fas-Associated Death Domain Protein
Fas-Associating Death Domain-Containing Protein
Growth-Inhibiting Gene 3 Protein
Mediator Of Receptor Induced Toxicity
Protein Fadd
Database Links Reactome: R-HSA-140534
Reactome: R-HSA-2562578
Reactome: R-HSA-3371378
Reactome: R-HSA-5213460
Reactome: R-HSA-5218900
Reactome: R-HSA-5357786
Reactome: R-HSA-5357905
Reactome: R-HSA-5675482
Reactome: R-HSA-69416
Reactome: R-HSA-75157
Reactome: R-HSA-75158
Reactome: R-HSA-9013957
Reactome: R-HSA-933543
Reactome: R-HSA-9693928
Alternative Antibody Names Anti-Fas-Associated Death Domain Protein antibody
Anti-Fas-Associating Death Domain-Containing Protein antibody
Anti-Growth-Inhibiting Gene 3 Protein antibody
Anti-Mediator Of Receptor Induced Toxicity antibody
Anti-Protein Fadd antibody
Anti-FADD antibody
Anti-MORT1 antibody
Anti-GIG3 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance