| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-Phospho-Translation initiation factor eIF-2B subunit epsilon-Ser540 is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: |
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen. |
| Concentration: |
1 mg/mL |
| Dilution Range: |
WB 1:500-2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
EIF2B5 |
| Gene ID: |
8893 |
| Uniprot ID: |
EI2BE_HUMAN |
| Specificity: |
This antibody detects endogenous levels of eIF2B-Epsilon (Phospho-Ser540) at Human, Mouse, Rat |
| Immunogen: |
Synthesized peptide derived from human eIF2B-Epsilon (Phospho-Ser540) |
| Post Translational Modifications | Phosphorylated at Ser-544 by DYRK2.this is required for subsequent phosphorylation by GSK3B. Phosphorylated on serine and threonine residues by GSK3B.phosphorylation inhibits its function. Polyubiquitinated, probably by NEDD4. |
| Function | Catalyzes the exchange of eukaryotic initiation factor 2-bound GDP for GTP. |
| Protein Name | Translation Initiation Factor Eif-2b Subunit EpsilonEif-2b Gdp-Gtp Exchange Factor Subunit Epsilon |
| Database Links | Reactome: R-HSA-72731 |
| Alternative Antibody Names | Anti-Translation Initiation Factor Eif-2b Subunit Epsilon antibodyAnti-Eif-2b Gdp-Gtp Exchange Factor Subunit Epsilon antibodyAnti-EIF2B5 antibodyAnti-EIF2BE antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
