• Immunohistochemistry analysis of paraffin-embedded human brain, using CKII-beta (Phospho-Ser209) Antibody. The picture on the right is blocked with the phospho peptide.
  • Western blot analysis of lysates from HUVEC cells, using CKII-beta (Phospho-Ser209) Antibody. The lane on the right is blocked with the phospho peptide.
  • Western blot analysis of HuvEc cells using Phospho-Casein Kinase II Beta (S209) Polyclonal Antibody

Anti-Phospho-CSNK2B-Ser209 antibody (166-215 aa) (STJ90892)

SKU:
STJ90892

Current Stock:
Host: Rabbit
Applications: WB/IHC/IF/ELISA
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-Phospho-Casein kinase II subunit beta-Ser209 (166-215 aa) is suitable for use in Western Blot, Immunohistochemistry, Immunofluorescence and ELISA research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/mL
Dilution Range: WB 1:500-1:2000
IHC 1:100-1:300
ELISA 1:40000
IF 1:50-200
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: CSNK2B
Gene ID: 1460
Uniprot ID: CSK2B_HUMAN
Immunogen Region: 166-215 aa
Specificity: Phospho-Casein Kinase II Beta (S209) Polyclonal Antibody detects endogenous levels of Casein Kinase II Beta protein only when phosphorylated at S209.
Immunogen: The antiserum was produced against synthesized peptide derived from the human CKII-beta around the phosphorylation site of Ser209 at the amino acid range 166-215
Function Regulatory subunit of casein kinase II/CK2. As part of the kinase complex regulates the basal catalytic activity of the alpha subunit a constitutively active serine/threonine-protein kinase that phosphorylates a large number of substrates containing acidic residues C-terminal to the phosphorylated serine or threonine. Participates in Wnt signaling. (Microbial infection) Upon infection with Epstein-Barr virus (EBV), the interaction with viral EBNA1 increases the association of CK2 with PML proteins, which increases PML phosphorylation by CK2, triggering the polyubiquitylation and degradation of PML. Seems to also suppress EBV reactivation by mediating ARK2N and JUN at the Z promoter which inhibits BZLF1 transcrition.
Protein Name Casein Kinase Ii Subunit Beta
Ck Ii Beta
Phosvitin
Protein G5a
Database Links Reactome: R-HSA-1483191
Reactome: R-HSA-201688
Reactome: R-HSA-2514853
Reactome: R-HSA-445144
Reactome: R-HSA-6798695
Reactome: R-HSA-6804756
Reactome: R-HSA-6814122
Reactome: R-HSA-8934903
Reactome: R-HSA-8939243
Reactome: R-HSA-8948751
Reactome: R-HSA-9755511
Cellular Localisation Nucleus
Alternative Antibody Names Anti-Casein Kinase Ii Subunit Beta antibody
Anti-Ck Ii Beta antibody
Anti-Phosvitin antibody
Anti-Protein G5a antibody
Anti-CSNK2B antibody
Anti-CK2N antibody
Anti-G5A antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance