Anti-Phospho-CLDN7-Tyr210 antibody (162-211 aa) (STJ90626)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenThe antiserum was produced against synthesized peptide derived from the human Claudin 7 around the phosphorylation site of Tyr210 at the amino acid range 162-211
General Information
| Short Description | Rabbit polyclonal anti-Phospho-Claudin-7-Tyr210 (162-211 aa) for use in WB and ELISA in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-1:2000ELISA 1:5000 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | CLDN7 |
| Gene ID | 1366 |
| Uniprot ID | CLD7_HUMAN |
| Immunogen | The antiserum was produced against synthesized peptide derived from the human Claudin 7 around the phosphorylation site of Tyr210 at the amino acid range 162-211 |
| Immunogen Region | 162-211 aa |
| Specificity | Phospho-Claudin-7 (Y210) Polyclonal Antibody detects endogenous levels of Claudin-7 protein only when phosphorylated at Y210. |
Additional Info
| Post Translational Modifications | Phosphorylated. |
| Function | Plays a major role in tight junction-specific obliteration of the intercellular space. |
| Protein Name | Claudin-7Cldn-7 |
| Database Links | Reactome: R-HSA-420029 |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane ProteinBasolateral Cell MembraneCell JunctionTight JunctionCo-Localizes With Epcam At The Basolateral Cell Membrane And Tight Junction |
| Alternative Antibody Names | Anti-Claudin-7 antibodyAnti-Cldn-7 antibodyAnti-CLDN7 antibodyAnti-CEPTRL2 antibodyAnti-CPETRL2 antibody |
Information sourced from Uniprot.org