Anti-Phospho-CDC6-Ser106 antibody [R01-0F2] (STJA0034152)
SPECIFICATIONS
ClonalityMonoclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenA synthetic phosphopeptide corresponding to residues surrounding Ser106 of human Cdc6
General Information
| Short Description | Rabbit monoclonal anti-Phospho-CDC6-Ser106 for use in WB in Human and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB |
| Host | Rabbit |
| Reactivity | Human/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | R01-0F2 |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 0.3 mg/mL |
| Purification | Affinity Purified |
| Dilution Range | WB 1:500-1:1000 |
| Formulation | 50mM Tris-Glycine (pH 7.4) , 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA |
| Storage Instruction | Store at 4°C short term. Aliquot and store at-20°C long term. Avoid freeze/thaw cycles. |
Target Information
| Gene Symbol | CDC6 |
| Gene ID | 990 |
| Uniprot ID | CDC6_HUMAN |
| Immunogen | A synthetic phosphopeptide corresponding to residues surrounding Ser106 of human Cdc6 |
Additional Info
| Post Translational Modifications | Ubiquitinated by the SCF(CCNF) E3 ubiquitin-protein ligase complex. |
| Function | Involved in the initiation of DNA replication. Also participates in checkpoint controls that ensure DNA replication is completed before mitosis is initiated. |
| Protein Name | Cell Division Control Protein 6 HomologCdc6-Related ProteinCdc18-Related ProteinHscdc18P62(Cdc6Hscdc6 |
| Database Links | Reactome: R-HSA-1362277Reactome: R-HSA-176187Reactome: R-HSA-68689Reactome: R-HSA-68867Reactome: R-HSA-68949Reactome: R-HSA-68962Reactome: R-HSA-69017Reactome: R-HSA-69205 |
| Cellular Localisation | NucleusCytoplasmThe Protein Is Nuclear In G1 And Cytoplasmic In S-Phase Cells |
| Alternative Antibody Names | Anti-Cell Division Control Protein 6 Homolog antibodyAnti-Cdc6-Related Protein antibodyAnti-Cdc18-Related Protein antibodyAnti-Hscdc18 antibodyAnti-P62(Cdc6 antibodyAnti-Hscdc6 antibodyAnti-CDC6 antibodyAnti-CDC18L antibody |
Information sourced from Uniprot.org