Anti-Phospho-CDC6-S54 antibody [S6MR] (STJ11102646)
SPECIFICATIONS
ClonalityMonoclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit monoclonal Phospho-Cdc6-S54 antibody for use in WB and ELISA in mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | S6MR |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:1000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.02% Sodium Azide, 0.05% BSA, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | CDC6 |
| Gene ID | 990 |
| Uniprot ID | CDC6_HUMAN |
| Immunogen Sequence | PLSPR |
| Specificity | A synthetic phosphorylated peptide around S54 of human Cdc6 (Q99741). |
Additional Info
| Post Translational Modifications | Ubiquitinated by the SCF(CCNF) E3 ubiquitin-protein ligase complex. |
| Function | Involved in the initiation of DNA replication. Also participates in checkpoint controls that ensure DNA replication is completed before mitosis is initiated. |
| Protein Name | Cell Division Control Protein 6 HomologCdc6-Related ProteinCdc18-Related ProteinHscdc18P62(Cdc6Hscdc6 |
| Database Links | Reactome: R-HSA-1362277Reactome: R-HSA-176187Reactome: R-HSA-68689Reactome: R-HSA-68867Reactome: R-HSA-68949Reactome: R-HSA-68962Reactome: R-HSA-69017Reactome: R-HSA-69205 |
| Cellular Localisation | NucleusCytoplasmThe Protein Is Nuclear In G1 And Cytoplasmic In S-Phase Cells |
| Alternative Antibody Names | Anti-Cell Division Control Protein 6 Homolog antibodyAnti-Cdc6-Related Protein antibodyAnti-Cdc18-Related Protein antibodyAnti-Hscdc18 antibodyAnti-P62(Cdc6 antibodyAnti-Hscdc6 antibodyAnti-CDC6 antibodyAnti-CDC18L antibody |
Information sourced from Uniprot.org