Anti-Phospho-CDC37-Ser13 antibody [R04-4I8] (STJA0035054)
SPECIFICATIONS
ClonalityMonoclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenA synthetic phosphopeptide corresponding to residues surrounding Ser13 of human Cdc37
General Information
| Short Description | Rabbit monoclonal anti-Phospho-CDC37-Ser13 for use in WB and IP in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IP |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | R04-4I8 |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 0.3 mg/mL |
| Purification | Affinity Purified |
| Dilution Range | WB 1:500-1:1000IP 1:20 |
| Formulation | 50mM Tris-Glycine (pH 7.4) , 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA |
| Storage Instruction | Store at 4°C short term. Aliquot and store at-20°C long term. Avoid freeze/thaw cycles. |
Target Information
| Gene Symbol | CDC37 |
| Gene ID | 11140 |
| Uniprot ID | CDC37_HUMAN |
| Immunogen | A synthetic phosphopeptide corresponding to residues surrounding Ser13 of human Cdc37 |
Additional Info
| Post Translational Modifications | Constitutively sumoylated by UBE2I. |
| Function | Co-chaperone that binds to numerous kinases and promotes their interaction with the Hsp90 complex, resulting in stabilization and promotion of their activity. Inhibits HSP90AA1 ATPase activity. |
| Protein Name | Hsp90 Co-Chaperone Cdc37Hsp90 Chaperone Protein Kinase-Targeting SubunitP50cdc37 Cleaved Into - Hsp90 Co-Chaperone Cdc37 - N-Terminally Processed |
| Database Links | Reactome: R-HSA-1227986Reactome: R-HSA-1236382Reactome: R-HSA-5637810Reactome: R-HSA-5675482Reactome: R-HSA-8863795Reactome: R-HSA-9013418Reactome: R-HSA-9634285Reactome: R-HSA-9652282Reactome: R-HSA-9664565Reactome: R-HSA-9665233Reactome: R-HSA-9665244Reactome: R-HSA-9665245Reactome: R-HSA-9665246Reactome: R-HSA-9665247Reactome: R-HSA-9665249Reactome: R-HSA-9665250Reactome: R-HSA-9665251Reactome: R-HSA-9665348Reactome: R-HSA-9665686Reactome: R-HSA-9665737 |
| Cellular Localisation | Cytoplasm |
| Alternative Antibody Names | Anti-Hsp90 Co-Chaperone Cdc37 antibodyAnti-Hsp90 Chaperone Protein Kinase-Targeting Subunit antibodyAnti-P50cdc37 Cleaved Into - Hsp90 Co-Chaperone Cdc37 - N-Terminally Processed antibodyAnti-CDC37 antibodyAnti-CDC37A antibody |
Information sourced from Uniprot.org