Anti-Phospho-CDC25A-Ser178 antibody (144-193 aa) (STJ90929)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenThe antiserum was produced against synthesized peptide derived from the human CDC25A around the phosphorylation site of Ser178 at the amino acid range 144-193
General Information
| Short Description | Rabbit polyclonal anti-Phospho-M-phase inducer phosphatase 1-Ser178 (144-193 aa) for use in WB, IHC, IF and ELISA in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IHC/IF/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-1:2000IHC 1:100-1:300ELISA 1:10000IF 1:50-200 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | CDC25A |
| Gene ID | 993 |
| Uniprot ID | MPIP1_HUMAN |
| Immunogen | The antiserum was produced against synthesized peptide derived from the human CDC25A around the phosphorylation site of Ser178 at the amino acid range 144-193 |
| Immunogen Region | 144-193 aa |
| Specificity | Phospho-Cdc25A (S178) Polyclonal Antibody detects endogenous levels of Cdc25A protein only when phosphorylated at S178. |
Additional Info
| Function | Tyrosine protein phosphatase which functions as a dosage-dependent inducer of mitotic progression. Directly dephosphorylates CDK1 and stimulates its kinase activity. Also dephosphorylates CDK2 in complex with cyclin-E, in vitro. |
| Protein Name | M-Phase Inducer Phosphatase 1Dual Specificity Phosphatase Cdc25a |
| Database Links | Reactome: R-HSA-1362277Reactome: R-HSA-156711Reactome: R-HSA-176187Reactome: R-HSA-5689880Reactome: R-HSA-69202Reactome: R-HSA-69273Reactome: R-HSA-69601Reactome: R-HSA-69656Reactome: R-HSA-8862803 |
| Cellular Localisation | |
| Alternative Antibody Names | Anti-M-Phase Inducer Phosphatase 1 antibodyAnti-Dual Specificity Phosphatase Cdc25a antibodyAnti-CDC25A antibody |
Information sourced from Uniprot.org