| Host: | Rabbit |
| Applications: | WB/IHC/IF/ELISA |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit polyclonal antibody anti-Phospho-M-phase inducer phosphatase 1-Ser178 (144-193 aa) is suitable for use in Western Blot, Immunohistochemistry, Immunofluorescence and ELISA research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: | 1 mg/mL |
| Dilution Range: | WB 1:500-1:2000 IHC 1:100-1:300 ELISA 1:10000 IF 1:50-200 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | CDC25A |
| Gene ID: | 993 |
| Uniprot ID: | MPIP1_HUMAN |
| Immunogen Region: | 144-193 aa |
| Specificity: | Phospho-Cdc25A (S178) Polyclonal Antibody detects endogenous levels of Cdc25A protein only when phosphorylated at S178. |
| Immunogen: | The antiserum was produced against synthesized peptide derived from the human CDC25A around the phosphorylation site of Ser178 at the amino acid range 144-193 |
| Function | Tyrosine protein phosphatase which functions as a dosage-dependent inducer of mitotic progression. Directly dephosphorylates CDK1 and stimulates its kinase activity. Also dephosphorylates CDK2 in complex with cyclin-E, in vitro. |
| Protein Name | M-Phase Inducer Phosphatase 1 Dual Specificity Phosphatase Cdc25a |
| Database Links | Reactome: R-HSA-1362277 Reactome: R-HSA-156711 Reactome: R-HSA-176187 Reactome: R-HSA-5689880 Reactome: R-HSA-69202 Reactome: R-HSA-69273 Reactome: R-HSA-69601 Reactome: R-HSA-69656 Reactome: R-HSA-8862803 |
| Alternative Antibody Names | Anti-M-Phase Inducer Phosphatase 1 antibody Anti-Dual Specificity Phosphatase Cdc25a antibody Anti-CDC25A antibody |
Information sourced from Uniprot.org