Anti-Phospho-ATRIP-Ser224 antibody (190-239 aa) (STJ90973)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenThe antiserum was produced against synthesized peptide derived from the human ATRIP around the phosphorylation site of Ser224 at the amino acid range 190-239
General Information
| Short Description | Rabbit polyclonal anti-Phospho-ATR-interacting protein-Ser224 (190-239 aa) for use in WB, IHC, IF and ELISA in Human, Rat and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IHC/IF/ELISA |
| Host | Rabbit |
| Reactivity | Human/Rat/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-1:2000IHC 1:100-1:300ELISA 1:10000IF 1:50-200 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | ATRIP |
| Gene ID | 84126 |
| Uniprot ID | ATRIP_HUMAN |
| Immunogen | The antiserum was produced against synthesized peptide derived from the human ATRIP around the phosphorylation site of Ser224 at the amino acid range 190-239 |
| Immunogen Region | 190-239 aa |
| Specificity | Phospho-ATRIP (S224) Polyclonal Antibody detects endogenous levels of ATRIP protein only when phosphorylated at S224. |
Additional Info
| Post Translational Modifications | Phosphorylated by ATR. |
| Function | Required for checkpoint signaling after DNA damage. Required for ATR expression, possibly by stabilizing the protein. |
| Protein Name | Atr-Interacting ProteinAtm And Rad3-Related-Interacting Protein |
| Database Links | Reactome: R-HSA-176187Reactome: R-HSA-5685938Reactome: R-HSA-5693607Reactome: R-HSA-5693616Reactome: R-HSA-6783310Reactome: R-HSA-6804756Reactome: R-HSA-69473Reactome: R-HSA-9709570 |
| Cellular Localisation | NucleusRedistributes To Discrete Nuclear Foci Upon Dna Damage |
| Alternative Antibody Names | Anti-Atr-Interacting Protein antibodyAnti-Atm And Rad3-Related-Interacting Protein antibodyAnti-ATRIP antibodyAnti-AGS1 antibody |
Information sourced from Uniprot.org