Anti-PHLDA2 antibody (1-152) (STJ28000)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal PHLDA2 (1-152) antibody for use in WB, IF, ICC and ELISA in human and mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IF/ICC/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:2000-1:4000IF/ICC:1:100-1:500ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | PHLDA2 |
| Gene ID | 7262 |
| Uniprot ID | PHLA2_HUMAN |
| Immunogen Region | 1-152 |
| Immunogen Sequence | MKSPDEVLREGELEKRSDSL FQLWKKKRGVLTSDRLSLFP ASPRARPKELRFHSILKVDC VERTGKYVYFTIVTTDHKEI DFRCAGESCWNAAIALALID FQNRRALQDFRSRQERTAPA APAEDAVAAAAAAPSEPSEP SRPSPQPKPRTP |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 1-152 of human PHLDA2 (NP_003302.1). |
Additional Info
| Tissue Specificity | Expressed in placenta and adult prostate gland. In placenta, it is present in all cells of the villous cytotrophoblast. The protein is absent in cells from hydatidiform moles. Hydatidiform mole is a gestation characterized by abnormal development of both fetus and trophoblast. The majority of hydatidiform moles are associated with an excess of paternal to maternal genomes and are likely to result from the abnormal expression of imprinted genes (at protein level). Expressed at low levels in adult liver and lung, and fetal liver. Expressed in adult brain and neuroblastoma, medullablastoma and glioblastoma cell lines. |
| Function | Plays a role in regulating placenta growth. May act via its PH domain that competes with other PH domain-containing proteins, thereby preventing their binding to membrane lipids. |
| Protein Name | Pleckstrin Homology-Like Domain Family A Member 2Beckwith-Wiedemann Syndrome Chromosomal Region 1 Candidate Gene C ProteinImprinted In Placenta And Liver ProteinTumor-Suppressing Stf Cdna 3 ProteinTumor-Suppressing Subchromosomal Transferable Fragment Candidate Gene 3 ProteinP17-Beckwith-Wiedemann Region 1 CP17-Bwr1c |
| Database Links | |
| Cellular Localisation | CytoplasmMembranePeripheral Membrane Protein |
| Alternative Antibody Names | Anti-Pleckstrin Homology-Like Domain Family A Member 2 antibodyAnti-Beckwith-Wiedemann Syndrome Chromosomal Region 1 Candidate Gene C Protein antibodyAnti-Imprinted In Placenta And Liver Protein antibodyAnti-Tumor-Suppressing Stf Cdna 3 Protein antibodyAnti-Tumor-Suppressing Subchromosomal Transferable Fragment Candidate Gene 3 Protein antibodyAnti-P17-Beckwith-Wiedemann Region 1 C antibodyAnti-P17-Bwr1c antibodyAnti-PHLDA2 antibodyAnti-BWR1C antibodyAnti-HLDA2 antibodyAnti-IPL antibodyAnti-TSSC3 antibody |
Information sourced from Uniprot.org