Anti-PHKA1/2 antibody (31-80 aa) (STJ95065)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenThe antiserum was produced against synthesized peptide derived from the human KPB1/2 at the amino acid range 31-80
General Information
| Short Description | Rabbit polyclonal anti-Phosphorylase b kinase regulatory subunit alpha, skeletal muscle isoform and Phosphorylase b kinase regulatory subunit alpha, liver isoform (31-80 aa) for use in WB, ELISA and IHC in Human, Mouse and Rat samples. Datasheet incl |
| Applications | WB/ELISA/IHC |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-2000IHC-P 1:50-300ELISA 2000-20000 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | PHKA2PHKA1 |
| Gene ID | 52565255 |
| Uniprot ID | KPB2_HUMANKPB1_HUMAN |
| Immunogen | The antiserum was produced against synthesized peptide derived from the human KPB1/2 at the amino acid range 31-80 |
| Immunogen Region | 31-80 aa |
| Specificity | PHKA1/2 Polyclonal Antibody detects endogenous levels of PHKA1/2 protein. |
Additional Info
| Post Translational Modifications | Although the final Cys may be farnesylated, the terminal tripeptide is probably not removed, and the C-terminus is not methylated. |
| Function | Phosphorylase b kinase catalyzes the phosphorylation of serine in certain substrates, including troponin I. The alpha chain may bind calmodulin. |
| Protein Name | Phosphorylase B Kinase Regulatory Subunit Alpha - Skeletal Muscle IsoformPhosphorylase Kinase Alpha M Subunit |
| Database Links | Reactome: R-HSA-70221 |
| Cellular Localisation | Cell MembraneLipid-AnchorCytoplasmic Side |
| Alternative Antibody Names | Anti-Phosphorylase B Kinase Regulatory Subunit Alpha - Skeletal Muscle Isoform antibodyAnti-Phosphorylase Kinase Alpha M Subunit antibodyAnti-PHKA1 antibodyAnti-PHKA antibody |
Information sourced from Uniprot.org