Anti-PHGDH antibody [SRM14489] (STJ11109219)
SPECIFICATIONS
ClonalityMonoclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenRecombinant protein (or fragment).This information is considered to be commercially sensitive.
General Information
| Short Description | Rabbit monoclonal PHGDH antibody for use in WB, IHC-P, IF, ICC and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IHC-P/IF/ICC/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | SRM14489 |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Purification | Affinity purification |
| Dilution Range | WB, 1:5000-1:20000IHC-P, 1:2000-1:8000IF/ICC, 1:400-1:1600ELISA, Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | PHGDH |
| Gene ID | 26227 |
| Uniprot ID | SERA_HUMAN |
| Immunogen | Recombinant protein (or fragment).This information is considered to be commercially sensitive. |
Additional Info
| Function | Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L-serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate and the reversible oxidation of (S)-malate to oxaloacetate. |
| Protein Name | D-3-Phosphoglycerate Dehydrogenase3-Pgdh2-Oxoglutarate ReductaseMalate Dehydrogenase |
| Database Links | Reactome: R-HSA-977347 |
| Cellular Localisation | |
| Alternative Antibody Names | Anti-D-3-Phosphoglycerate Dehydrogenase antibodyAnti-3-Pgdh antibodyAnti-2-Oxoglutarate Reductase antibodyAnti-Malate Dehydrogenase antibodyAnti-PHGDH antibodyAnti-PGDH3 antibody |
Information sourced from Uniprot.org