Anti-PGM1 antibody (1-300) (STJ28225)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal PGM1 (1-300) antibody for use in WB and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | PGM1 |
| Gene ID | 5236 |
| Uniprot ID | PGM1_HUMAN |
| Immunogen Region | 1-300 |
| Immunogen Sequence | MVKIVTVKTQAYQDQKPGTS GLRKRVKVFQSSANYAENFI QSIISTVEPAQRQEATLVVG GDGRFYMKEAIQLIARIAAA NGIGRLVIGQNGILSTPAVS CIIRKIKAIGGIILTASHNP GGPNGDFGIKFNISNGGPAP EAITDKIFQISKTIEEYAVC PDLKVDLGVLGKQQFDLENK FKPFTVEIVDSVEAYATMLR SIFDFSALKELLSGPNRLKI RIDAMHGVVGPYVKKILCE |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 1-300 of human PGM1 (NP_002624.2). |
Additional Info
| Post Translational Modifications | Phosphorylation at Thr-467 by PAK1 significantly enhances enzymatic activity. |
| Function | Catalyzes the reversible isomerization of alpha-D-glucose 1-phosphate to alpha-D-glucose 6-phosphate. The mechanism proceeds via the intermediate compound alpha-D-glucose 1,6-bisphosphate (Probable). This enzyme participates in both the breakdown and synthesis of glucose. |
| Protein Name | Phosphoglucomutase-1Pgm 1Glucose Phosphomutase 1 |
| Database Links | Reactome: R-HSA-3322077Reactome: R-HSA-5609974Reactome: R-HSA-6798695Reactome: R-HSA-70221Reactome: R-HSA-70370 |
| Cellular Localisation | Isoform 1: Cytoplasm |
| Alternative Antibody Names | Anti-Phosphoglucomutase-1 antibodyAnti-Pgm 1 antibodyAnti-Glucose Phosphomutase 1 antibodyAnti-PGM1 antibody |
Information sourced from Uniprot.org