| Host: |
Rabbit |
| Applications: |
CM/ELISA/ICC/IF/IHC/WB |
| Reactivity: |
Human/Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-PGCF (C-Term) is suitable for use in Confocal Microscopy, ELISA, Immunocytochemistry, Immunofluorescence, Immunohistochemistry and Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Purification: |
Affinity Purified |
| Concentration: |
0.75-1.20 µg/µl |
| Dilution Range: |
WB: 1:500DB: 1:10, 000ELISA: 1:10, 000IHC: 1:200ICC: 1:200IF: 1:200CFM: 1:200 |
| Storage Instruction: |
Store at-20°C for long term storage. Avoid freeze-thaw cycles. |
| Gene Symbol: |
Gucy2f |
| Gene ID: |
116556 |
| Uniprot ID: |
GUC2F_RAT |
| Immunogen Region: |
C-Term |
| Immunogen: |
Synthetic C-terminal peptide corresponding to unique amino acid sequences on Particulate Guanylyl Cyclase F protein. |
| Tissue Specificity | Expressed only in the eye. |
| Post Translational Modifications | There are 9 conserved cysteine residues in sensory guanylate cyclases, 6 in the extracellular domain, which may be involved in intra- or interchain disulfide bonds. |
| Function | Responsible for the synthesis of cyclic GMP (cGMP) in rods and cones of photoreceptors. Plays an essential role in phototransduction, by mediating cGMP replenishment. May also participate in the trafficking of membrane-asociated proteins to the photoreceptor outer segment membrane. |
| Protein Name | Retinal Guanylyl Cyclase 2Retgc-2Guanylate Cyclase 2f - RetinalGuanylate Cyclase FGc-FRod Outer Segment Membrane Guanylate Cyclase 2Ros-Gc2 |
| Database Links | Reactome: R-RNO-2514859 |
| Cellular Localisation | MembraneSingle-Pass Type I Membrane ProteinPhotoreceptor Outer Segment Membrane |
| Alternative Antibody Names | Anti-Retinal Guanylyl Cyclase 2 antibodyAnti-Retgc-2 antibodyAnti-Guanylate Cyclase 2f - Retinal antibodyAnti-Guanylate Cyclase F antibodyAnti-Gc-F antibodyAnti-Rod Outer Segment Membrane Guanylate Cyclase 2 antibodyAnti-Ros-Gc2 antibodyAnti-Gucy2f antibodyAnti-Guc2f antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
