Anti-PGAM1 antibody (1-254aa) [AT1G4] (STJA0041729)
SPECIFICATIONS
ClonalityMonoclonal
HostMouse
ConjugationUnconjugated
IsotypeIgG2aL
ImmunogenRecombinant human PGAM1 (1-254aa) purified from E. coli
General Information
| Short Description | Mouse monoclonal anti-PGAM1 (1-254aa) for use in ELISA, WB, ICC and IF in Human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | ELISA/WB/ICC/IF |
| Host | Mouse |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | AT1G4 |
| Isotype | IgG2aL |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | By protein-A affinity chromatography |
| Formulation | Liquid in phosphate-Buffered Saline (pH 7.4) with 0.02% Sodium Azide, 10% Glycerol |
| Storage Instruction | For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | PGAM1 |
| Gene ID | 5223 |
| Uniprot ID | PGAM1_HUMAN |
| Accession Number | NP_002620 |
| Immunogen | Recombinant human PGAM1 (1-254aa) purified from E. coli |
| Immunogen Region | 1-254aa |
Additional Info
| Tissue Specificity | Expressed in the liver and brain. Not found in the muscle. |
| Post Translational Modifications | Acetylated at Lys-253, Lys-253 and Lys-254 under high glucose condition. Acetylation increases catalytic activity. Under glucose restriction SIRT1 levels dramatically increase and it deacetylates the enzyme. |
| Function | Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglyceratea crucial step in glycolysis, by using 2,3-bisphosphoglycerate. Also catalyzes the interconversion of (2R)-2,3-bisphosphoglycerate and (2R)-3-phospho-glyceroyl phosphate. |
| Protein Name | Phosphoglycerate Mutase 1Bpg-Dependent Pgam 1Phosphoglycerate Mutase Isozyme BPgam-B |
| Database Links | Reactome: R-HSA-6798695Reactome: R-HSA-70171Reactome: R-HSA-70263 |
| Cellular Localisation | |
| Alternative Antibody Names | Anti-Phosphoglycerate Mutase 1 antibodyAnti-Bpg-Dependent Pgam 1 antibodyAnti-Phosphoglycerate Mutase Isozyme B antibodyAnti-Pgam-B antibodyAnti-PGAM1 antibodyAnti-PGAMA antibodyAnti-CDABP0006 antibody |
Information sourced from Uniprot.org