Anti-PFKP antibody (336-540) (STJ11103617)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal PFKP (336-540) antibody for use in WB, IHC-P, IF, ICC and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IHC-P/IF/ICC/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:1000IHC-P:1:100-1:200IF/ICC:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.05% Proclin300, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | PFKP |
| Gene ID | 5214 |
| Uniprot ID | PFKAP_HUMAN |
| Immunogen Region | 336-540 |
| Immunogen Sequence | ATPDTPACVVSLNGNHAVRL PLMECVQMTQDVQKAMDERR FQDAVRLRGRSFAGNLNTYK RLAIKLPDDQIPKTNCNVAV INVGAPAAGMNAAVRSAVRV GIADGHRMLAIYDGFDGFAK GQIKEIGWTDVGGWTGQGGS ILGTKRVLPGKYLEEIATQM RTHSINALLIIGGFEAYLGL LELSAAREKHEEFCVPMVMV PATVS |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 336-540 of human PFKP (NP_002618.1). |
Additional Info
| Post Translational Modifications | Phosphorylation at Ser-386 promotes interaction with ATG4B. GlcNAcylation decreases enzyme activity. |
| Function | Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis. |
| Protein Name | Atp-Dependent 6-Phosphofructokinase - Platelet TypeAtp-PfkPfk-P6-Phosphofructokinase Type CPhosphofructo-1-Kinase Isozyme CPfk-CPhosphohexokinase |
| Database Links | Reactome: R-HSA-70171 |
| Cellular Localisation | Cytoplasm |
| Alternative Antibody Names | Anti-Atp-Dependent 6-Phosphofructokinase - Platelet Type antibodyAnti-Atp-Pfk antibodyAnti-Pfk-P antibodyAnti-6-Phosphofructokinase Type C antibodyAnti-Phosphofructo-1-Kinase Isozyme C antibodyAnti-Pfk-C antibodyAnti-Phosphohexokinase antibodyAnti-PFKP antibodyAnti-PFKF antibody |
Information sourced from Uniprot.org