Anti-PFAS antibody (1-300) (STJ119609)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal PFAS (1-300) antibody for use in WB and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | PFAS |
| Gene ID | 5198 |
| Uniprot ID | PUR4_HUMAN |
| Immunogen Region | 1-300 |
| Immunogen Sequence | MSPVLHFYVRPSGHEGAAPG HTRRKLQGKLPELQGVETEL CYNVNWTAEALPSAEETKKL MWLFGCPLLLDDVARESWLL PGSNDLLLEVGPRLNFSTPT STNIVSVCRATGLGPVDRVE TTRRYRLSFAHPPSAEVEAI ALATLHDRMTEQHFPHPIQS FSPESMPEPLNGPINILGEG RLALEKANQELGLALDSWDL DFYTKRFQELQRNPSTVEAF DLAQSNSEHSRHWFFKGQL |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 1-300 of human PFAS (NP_036525.1). |
Additional Info
| Function | Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. |
| Protein Name | Phosphoribosylformylglycinamidine SynthaseFgam SynthaseFgamsFormylglycinamide Ribonucleotide AmidotransferaseFgar AmidotransferaseFgar-AtFormylglycinamide Ribotide AmidotransferasePhosphoribosylformylglycineamide Amidotransferase |
| Database Links | Reactome: R-HSA-73817 |
| Cellular Localisation | Cytoplasm |
| Alternative Antibody Names | Anti-Phosphoribosylformylglycinamidine Synthase antibodyAnti-Fgam Synthase antibodyAnti-Fgams antibodyAnti-Formylglycinamide Ribonucleotide Amidotransferase antibodyAnti-Fgar Amidotransferase antibodyAnti-Fgar-At antibodyAnti-Formylglycinamide Ribotide Amidotransferase antibodyAnti-Phosphoribosylformylglycineamide Amidotransferase antibodyAnti-PFAS antibodyAnti-KIAA0361 antibody |
Information sourced from Uniprot.org