Anti-PEX7 antibody (204-253 aa) (STJ95043)

SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenThe antiserum was produced against synthesized peptide derived from the human PEX7 at the amino acid range 204-253
STJ95043
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General Information

Short DescriptionRabbit polyclonal anti-Peroxisomal targeting signal 2 receptor (204-253 aa) for use in WB, IHC, IF and ELISA in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents.
ApplicationsWB/IHC/IF/ELISA
HostRabbit
ReactivityHuman/Mouse/Rat
NoteSTRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Product Properties

ClonalityPolyclonal
IsotypeIgG
ConjugationUnconjugated
Concentration1 mg/mL
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Dilution RangeWB 1:500-1:2000
IHC 1:100-1:300
ELISA 1:40000
IF 1:50-200
FormulationLiquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Storage InstructionStore at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.

Target Information

Gene SymbolPEX7
Gene ID5191
Uniprot IDPEX7_HUMAN
ImmunogenThe antiserum was produced against synthesized peptide derived from the human PEX7 at the amino acid range 204-253
Immunogen Region204-253 aa
SpecificityPeroxin 7 Polyclonal Antibody detects endogenous levels of Peroxin 7 protein.

Additional Info

Function Receptor required for the peroxisomal import of proteins containing a C-terminal PTS2-type peroxisomal targeting signal. Specifically binds to cargo proteins containing a PTS2 peroxisomal targeting signal in the cytosol. Cargo protein-binding triggers interaction with PEX5 and formation of a ternary complex composed of PEX5 and PEX7 along with PTS2-containing cargo proteins, which is tranlocated into peroxisomes by passing through the PEX13-PEX14 docking complex.
Protein Name Peroxisomal Targeting Signal 2 Receptor
Pts2 Receptor
Peroxin-7
Database Links Reactome: R-HSA-9033241
Cellular Localisation Cytoplasm
Cytosol
Peroxisome Matrix
Translocated Into The Peroxisome Matrix Together With Pts2-Containing Cargo Proteins And Pex5
Alternative Antibody Names Anti-Peroxisomal Targeting Signal 2 Receptor antibody
Anti-Pts2 Receptor antibody
Anti-Peroxin-7 antibody
Anti-PEX7 antibody
Anti-PTS2R antibody

Information sourced from Uniprot.org

Citations

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