Anti-Pescadillo antibody (N-Term) (STJ70378)

SPECIFICATIONS
ClonalityPolyclonal
HostGoat
ConjugationUnconjugated
IsotypeIgG
STJ70378-100
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General Information

Short DescriptionGoat polyclonal antibody anti-Pescadillo (N-Term) is suitable for use in ELISA, Western Blot and Immunohistochemistry research applications.
ApplicationsPep-ELISA/WB/IHC
HostGoat
ReactivityHuman/Mouse/Pig/Cow
NoteSTRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Product Properties

ClonalityPolyclonal
IsotypeIgG
ConjugationUnconjugated
Concentration0.5 mg/mL
PurificationPurified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Dilution RangePeptide ELISA: antibody detection limit dilution 1:32000.
WB: Approx 70kDa band observed in HeLa lysate (calculated MW of 68kDa according to NP_055118). Recommended concentration: 1-3µg/ml.
IHC: In paraffin embedded Human Testis shows nucleol
Formulation0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA
Storage InstructionStore at-20°C on receipt and minimise freeze-thaw cycles.

Target Information

Gene SymbolPES1
Gene ID23481
Uniprot IDPESC_HUMAN
Accession NumberNP_055118.1
Immunogen RegionN-Term
Immunogen SequenceGGLEKKKYERGSA

Additional Info

Post Translational Modifications Sumoylated.
Function Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome.
Protein Name Pescadillo Homolog
Database Links Reactome: R-HSA-6791226
Cellular Localisation Nucleus
Nucleolus
Nucleoplasm
Chromosome
Appears To Localize To The Periphery Of Metaphase Chromosomes During Mitosis And To The Prenucleolar Bodies That Form In Mitotic Cells Prior To The Actual Nucleoli
Alternative Antibody Names Anti-Pescadillo Homolog antibody
Anti-PES1 antibody

Information sourced from Uniprot.org

Citations

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