Anti-Perpherin antibody (STJA0040628)
SPECIFICATIONS
ClonalityPolyclonal
HostChicken
ConjugationUnconjugated
IsotypeIgY
ImmunogenRecombinant rat peripherin expressed in Escherichia coli
General Information
| Short Description | Chicken polyclonal anti-Perpherin for use in IHC, ICC and WB in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | IHC/ICC/WB |
| Host | Chicken |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgY |
| Conjugation | Unconjugated |
| Concentration | 2 mg/mL |
| Purification | IgY Fraction |
| Dilution Range | WB 1:2000-1:5000IHC 1:2000-1:5000ICC 1:2000-1:5000 |
| Formulation | Phosphate-buffered (10 mM) isotonic (0.9%, w/v) saline (PBS" pH 7.2) with bovine serum albumin (BSA, 0.5%) added to prevent absorption to the plastic and sodium azide (0.02%, w/v) added as a preservative" |
| Storage Instruction | Store at 4°C in the dark. Under these conditions, the antibodies should have a shelf life of at least twelve months, provided they remain sterile. For longer term storage, aliquot and freeze to avoid freeze-thaw of the antibody. |
Target Information
| Gene Symbol | PRPH |
| Gene ID | 5630 |
| Uniprot ID | PERI_HUMAN |
| Immunogen | Recombinant rat peripherin expressed in Escherichia coli |
| Immunogen Sequence | Rat |
Additional Info
| Post Translational Modifications | Phosphorylated.phosphorylation increases after nerve injury in regenerating neurons. |
| Function | Class-III neuronal intermediate filament protein. May form an independent structural network without the involvement of other neurofilaments or may cooperate with the neuronal intermediate filament proteins NEFL, NEFH, NEFM and INA to form a filamentous network. Assembly of the neuronal intermediate filaments may be regulated by RAB7A. Plays a role in the development of unmyelinated sensory neurons. May be involved in axon elongation and axon regeneration after injury. Inhibits neurite extension in type II spiral ganglion neurons in the cochlea. |
| Protein Name | PeripherinNeurofilament 4 |
| Database Links | |
| Cellular Localisation | CytoplasmCytoskeletonCell ProjectionAxonPerikaryon |
| Alternative Antibody Names | Anti-Peripherin antibodyAnti-Neurofilament 4 antibodyAnti-PRPH antibodyAnti-NEF4 antibodyAnti-PRPH1 antibody |
Information sourced from Uniprot.org