Anti-Peroxiredoxin 2 antibody (C-Term) (STJ70943)
SPECIFICATIONS
ClonalityPolyclonal
HostGoat
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Goat polyclonal antibody anti-Peroxiredoxin 2 (C-Term) is suitable for use in ELISA and Western Blot research applications. |
| Applications | Pep-ELISA/WB |
| Host | Goat |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 0.5 mg/mL |
| Purification | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Dilution Range | Peptide ELISA: antibody detection limit dilution 1:16000.WB: Approx 20-22kDa band observed in Human Brain lysates (calculated MW of 21.9kDa according to NP_005800.3). Recommended concentration: 0.3-1µg/ml. Primary incubation was 1 hour. |
| Formulation | 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA |
| Storage Instruction | Store at-20°C on receipt and minimise freeze-thaw cycles. |
Target Information
| Gene Symbol | PRDX2 |
| Gene ID | 7001 |
| Uniprot ID | PRDX2_HUMAN |
| Accession Number | NP_005800.3; NP_859427.1 |
| Immunogen Region | C-Term |
| Immunogen Sequence | NVDDSKEYFSKHN |
| Specificity | This antibody is expected to recognise isoforms a and b only (NP_005800.3 and NP_859427.1 respectively). |
Additional Info
| Function | Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides and as sensor of hydrogen peroxide-mediated signaling events. Might participate in the signaling cascades of growth factors and tumor necrosis factor-alpha by regulating the intracellular concentrations of H(2)O(2). |
| Protein Name | Peroxiredoxin-2Natural Killer Cell-Enhancing Factor BNkef-BPrpThiol-Specific Antioxidant ProteinTsaThioredoxin Peroxidase 1Thioredoxin-Dependent Peroxide Reductase 1Thioredoxin-Dependent Peroxiredoxin 2 |
| Database Links | Reactome: R-HSA-3299685Reactome: R-HSA-5628897Reactome: R-HSA-8862803 |
| Cellular Localisation | Cytoplasm |
| Alternative Antibody Names | Anti-Peroxiredoxin-2 antibodyAnti-Natural Killer Cell-Enhancing Factor B antibodyAnti-Nkef-B antibodyAnti-Prp antibodyAnti-Thiol-Specific Antioxidant Protein antibodyAnti-Tsa antibodyAnti-Thioredoxin Peroxidase 1 antibodyAnti-Thioredoxin-Dependent Peroxide Reductase 1 antibodyAnti-Thioredoxin-Dependent Peroxiredoxin 2 antibodyAnti-PRDX2 antibodyAnti-NKEFB antibodyAnti-TDPX1 antibody |
Information sourced from Uniprot.org