Anti-Perilipin-2 antibody [SRM14429] (STJ11109159)

SPECIFICATIONS
ClonalityMonoclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenRecombinant protein (or fragment).This information is considered to be commercially sensitive.
STJ11109159
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General Information

Short DescriptionRabbit monoclonal Perilipin-2 antibody for use in WB, IHC-P, IF, ICC and ELISA in human samples. Datasheet included with dilution recommendations, and related reagents.
ApplicationsWB/IHC-P/IF/ICC/ELISA
HostRabbit
ReactivityHuman
NoteSTRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Product Properties

ClonalityMonoclonal
Clone IDSRM14429
IsotypeIgG
ConjugationUnconjugated
PurificationAffinity purification
Dilution RangeWB, 1:1000-1:6000
IHC-P, 1:500-1:1000
IF/ICC, 1:50-1:200
ELISA, Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements.
Storage InstructionStore at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.

Target Information

Gene SymbolPLIN2
Gene ID123
Uniprot IDPLIN2_HUMAN
ImmunogenRecombinant protein (or fragment).This information is considered to be commercially sensitive.

Additional Info

Tissue Specificity Milk lipid globules.
Post Translational Modifications Acylated.primarily with C14, C16 and C18 fatty acids. Phosphorylation at Tyr-232 by isoform 1 of CHKA (CHKalpha2) promotes dissociation from lipid droplets: dissociation is followed by recruitment of autophagosome machinery to lipid droplets and subsequent lipid droplet lipolysis. Polyubiquitination of Nt-acetylatable A-PLIN2 by MARCHF6 lead to degradation by 26S proteasomes.
Function Structural component of lipid droplets, which is required for the formation and maintenance of lipid storage droplets.
Protein Name Perilipin-2
Adipophilin
Adipose Differentiation-Related Protein
Adrp
Database Links Reactome: R-HSA-1989781
Reactome: R-HSA-9613354
Reactome: R-HSA-9613829
Reactome: R-HSA-9615710
Reactome: R-HSA-9841922
Cellular Localisation Membrane
Peripheral Membrane Protein
Lipid Droplet
Alternative Antibody Names Anti-Perilipin-2 antibody
Anti-Adipophilin antibody
Anti-Adipose Differentiation-Related Protein antibody
Anti-Adrp antibody
Anti-PLIN2 antibody
Anti-ADFP antibody

Information sourced from Uniprot.org

Citations

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