![Anti-Perforin antibody [MRQ-23] (STJ16100415)](https://cdn11.bigcommerce.com/s-zso2xnchw9/images/stencil/124x110/products/149132/346753/STJ16100415_1__99087.1681998849.jpg?c=1 "Anti-Perforin antibody [MRQ-23] (STJ16100415)")
![Anti-Perforin antibody [MRQ-23] (STJ16100415)](https://cdn11.bigcommerce.com/s-zso2xnchw9/images/stencil/1280x1280/products/149132/346753/STJ16100415_1__99087.1681998849.jpg?c=1 "Anti-Perforin antibody [MRQ-23] (STJ16100415)")
Anti-Perforin antibody [MRQ-23] (STJ16100415)
SPECIFICATIONS
ClonalityMonoclonal
HostMouse
ConjugationUnconjugated
IsotypeIgG1
General Information
| Short Description | Mouse monoclonal anti-Perforin for use in IHC-P in Human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | IHC-P |
| Host | Mouse |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | MRQ-23 |
| Isotype | IgG1 |
| Conjugation | Unconjugated |
| Dilution Range | IHC 1:10 – 1:50 |
| Formulation | Tris Buffer, pH 7.3-7.7, containing 1% BSA and <0.1% Sodium Azide |
| Storage Instruction | Store at 2-8°C for up to 1-year, upon receipt. |
Target Information
Additional Info
| Background | Perforin is a pore-forming protein that leads to osmotic lysis of the target cells and subsequently enables granzymes to enter the target cells and activate apoptosis, the cell death program. The expression of perforin is reportedly upregulated in activated CD8+ T-cells, natural killer cells and some CD4+ T-cells. |
Information sourced from Uniprot.org