Anti-Pepsinogen II antibody [L10CC10] (STJ16100795)
SPECIFICATIONS
ClonalityMonoclonal
HostMouse
ConjugationUnconjugated
IsotypeIgG1
ImmunogenPepsinogen II purified from human tissue
General Information
| Short Description | Mouse monoclonal anti-Pepsinogen II for use in IHC-F, IHC-P, WB and ELISA in Human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | IHC-F/IHC-P/WB/ELISA |
| Host | Mouse |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | L10CC10 |
| Isotype | IgG1 |
| Conjugation | Unconjugated |
| Concentration | 100 Mu g/mL |
| Formulation | PBS with 1% BSA & 0.09% sodium azide |
| Storage Instruction | Store at 2-8Β°C for up to 1-year, upon receipt. |
Target Information
| Immunogen | Pepsinogen II purified from human tissue |
Additional Info
| Background | The antibody is specific to human pepsinogen II and has no crossreactivity to human pepsinogen I. Pepsinogen II is a group of precursor molecules for pepsin. These proteins are secreted into the gastric lumen by the pyloric glands of the gastric antrum and also by the chief and neck cells of the gastric corpus (oxyntic mucosa). Negative immunohistochemical reaction for pepsinogen I (right) but positive reaction for pepsinogen II (left) is a typical sign of the antral mucosa and, in the presence of atrophic gastritis, this staining pattern indicates that the positive glands and cells are metaplastic and βpyloricβ in differentiation (so called pseudopyloric metaplasia). |
Information sourced from Uniprot.org