Anti-PEDF antibody [R03-5R9] (STJA0036774)
SPECIFICATIONS
ClonalityMonoclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenA synthesized peptide derived from human PEDF
General Information
| Short Description | Rabbit monoclonal anti-PEDF for use in WB and FC in Human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/FC |
| Host | Rabbit |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | R03-5R9 |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Purification | Affinity Chromatography |
| Dilution Range | WB 1:500-1:1000FC 1:50-1:100 |
| Formulation | Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Storage Instruction | Store at 4°C short term. Aliquot and store at-20°C long term. Avoid freeze/thaw cycles. |
Target Information
| Gene Symbol | SERPINF1 |
| Gene ID | 5176 |
| Uniprot ID | PEDF_HUMAN |
| Immunogen | A synthesized peptide derived from human PEDF |
Additional Info
| Tissue Specificity | Retinal pigment epithelial cells and blood plasma. |
| Post Translational Modifications | The N-terminus is blocked. Extracellular phosphorylation enhances antiangiogenic activity. N- and O-glycosylated. O-glycosylated with a core 1 or possibly core 8 glycan. |
| Function | Neurotrophic protein.induces extensive neuronal differentiation in retinoblastoma cells. Potent inhibitor of angiogenesis. As it does not undergo the S (stressed) to R (relaxed) conformational transition characteristic of active serpins, it exhibits no serine protease inhibitory activity. |
| Protein Name | Pigment Epithelium-Derived FactorPedfCell Proliferation-Inducing Gene 35 ProteinEpc-1Serpin F1 |
| Database Links | |
| Cellular Localisation | SecretedMelanosomeEnriched In Stage I Melanosomes |
| Alternative Antibody Names | Anti-Pigment Epithelium-Derived Factor antibodyAnti-Pedf antibodyAnti-Cell Proliferation-Inducing Gene 35 Protein antibodyAnti-Epc-1 antibodyAnti-Serpin F1 antibodyAnti-SERPINF1 antibodyAnti-PEDF antibodyAnti-PIG35 antibody |
Information sourced from Uniprot.org