Anti-PEAK1 antibody (111-160 aa) (STJ95636)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenThe antiserum was produced against synthesized peptide derived from the human SGK269 at the amino acid range 111-160
General Information
| Short Description | Rabbit polyclonal anti-Inactive tyrosine-protein kinase PEAK1 (111-160 aa) for use in WB and IHC in Human, Rat and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IHC |
| Host | Rabbit |
| Reactivity | Human/Rat/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-2000IHC-P 1:50-300 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | PEAK1 |
| Gene ID | 79834 |
| Uniprot ID | PEAK1_HUMAN |
| Immunogen | The antiserum was produced against synthesized peptide derived from the human SGK269 at the amino acid range 111-160 |
| Immunogen Region | 111-160 aa |
| Specificity | SgK269 Polyclonal Antibody detects endogenous levels of SgK269 protein. |
Additional Info
| Function | Probable catalytically inactive kinase. Scaffolding protein that regulates the cytoskeleton to control cell spreading and migration by modulating focal adhesion dynamics. Acts as a scaffold for mediating EGFR signaling. |
| Protein Name | Inactive Tyrosine-Protein Kinase Peak1Pseudopodium-Enriched Atypical Kinase 1Sugen Kinase 269Tyrosine-Protein Kinase Sgk269 |
| Database Links | Reactome: R-HSA-9013420Reactome: R-HSA-9013424 |
| Cellular Localisation | CytoplasmCytoskeletonCell JunctionFocal AdhesionColocalizes With F-Actin In Serum-Rich MediumActin Colocalization Is Reduced During Serum Starvation |
| Alternative Antibody Names | Anti-Inactive Tyrosine-Protein Kinase Peak1 antibodyAnti-Pseudopodium-Enriched Atypical Kinase 1 antibodyAnti-Sugen Kinase 269 antibodyAnti-Tyrosine-Protein Kinase Sgk269 antibodyAnti-PEAK1 antibodyAnti-KIAA2002 antibody |
Information sourced from Uniprot.org