| Short Description : | Rabbit polyclonal anti-Inactive tyrosine-protein kinase PEAK1 (111-160 aa) for use in WB and IHC in Human, Rat and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications: | WB/IHC |
| Host: | Rabbit |
| Reactivity: | Human/Rat/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Isotype: | IgG |
| Conjugation: | Unconjugated |
| Concentration: | 1 mg/mL |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range: | WB 1:500-2000IHC-P 1:50-300 |
| Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | PEAK1 |
| Gene ID: | 79834 |
| Uniprot ID: | PEAK1_HUMAN |
| Immunogen: | The antiserum was produced against synthesized peptide derived from the human SGK269 at the amino acid range 111-160 |
| Immunogen Region: | 111-160 aa |
| Specificity: | SgK269 Polyclonal Antibody detects endogenous levels of SgK269 protein. |
| Function | Probable catalytically inactive kinase. Scaffolding protein that regulates the cytoskeleton to control cell spreading and migration by modulating focal adhesion dynamics. Acts as a scaffold for mediating EGFR signaling. |
| Protein Name | Inactive Tyrosine-Protein Kinase Peak1Pseudopodium-Enriched Atypical Kinase 1Sugen Kinase 269Tyrosine-Protein Kinase Sgk269 |
| Database Links | Reactome: R-HSA-9013420Reactome: R-HSA-9013424 |
| Cellular Localisation | CytoplasmCytoskeletonCell JunctionFocal AdhesionColocalizes With F-Actin In Serum-Rich MediumActin Colocalization Is Reduced During Serum Starvation |
| Alternative Antibody Names | Anti-Inactive Tyrosine-Protein Kinase Peak1 antibodyAnti-Pseudopodium-Enriched Atypical Kinase 1 antibodyAnti-Sugen Kinase 269 antibodyAnti-Tyrosine-Protein Kinase Sgk269 antibodyAnti-PEAK1 antibodyAnti-KIAA2002 antibody |
Information sourced from Uniprot.org
