Anti-PDYN antibody (201-250 aa) (STJ192589)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from the human protein at the amino acid range 201-250
General Information
| Short Description | Rabbit polyclonal anti-Proenkephalin-B (201-250 aa) for use in WB and ELISA in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-2000ELISA 1:5000-20000 |
| Formulation | Liquid in PBS containing 50% Glycerol and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | PDYN |
| Gene ID | 5173 |
| Uniprot ID | PDYN_HUMAN |
| Immunogen | Synthesized peptide derived from the human protein at the amino acid range 201-250 |
| Immunogen Region | 201-250 aa |
| Specificity | PDYN Polyclonal Antibody detects endogenous levels of protein. |
Additional Info
| Function | Leu-enkephalins compete with and mimic the effects of opiate drugs. They play a role in a number of physiologic functions, including pain perception and responses to stress. Dynorphin peptides differentially regulate the kappa opioid receptor. Dynorphin A(1-13) has a typical opioid activity, it is 700 times more potent than Leu-enkephalin. Leumorphin has a typical opioid activity and may have anti-apoptotic effect. |
| Protein Name | Proenkephalin-BBeta-Neoendorphin-DynorphinPreprodynorphin Cleaved Into - Alpha-Neoendorphin - Beta-Neoendorphin - Big DynorphinBig Dyn - Dynorphin A(1-17Dyn-A17Dynorphin A - Dynorphin A(1-13 - Dynorphin A(1-8 - Leu-Enkephalin - RimorphinDynorphin BDyn-BDynorphin B(1-13 - LeumorphinDynorphin B-29 |
| Database Links | Reactome: R-HSA-111885Reactome: R-HSA-202040Reactome: R-HSA-375276Reactome: R-HSA-418594 |
| Cellular Localisation | Secreted |
| Alternative Antibody Names | Anti-Proenkephalin-B antibodyAnti-Beta-Neoendorphin-Dynorphin antibodyAnti-Preprodynorphin Cleaved Into - Alpha-Neoendorphin - Beta-Neoendorphin - Big Dynorphin antibodyAnti-Big Dyn - Dynorphin A(1-17 antibodyAnti-Dyn-A17 antibodyAnti-Dynorphin A - Dynorphin A(1-13 - Dynorphin A(1-8 - Leu-Enkephalin - Rimorphin antibodyAnti-Dynorphin B antibodyAnti-Dyn-B antibodyAnti-Dynorphin B(1-13 - Leumorphin antibodyAnti-Dynorphin B-29 antibodyAnti-PDYN antibody |
Information sourced from Uniprot.org