Anti-PDXK antibody (1-312) (STJ28770)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal PDXK (1-312) antibody for use in WB, IF, ICC and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IF/ICC/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:1000IF/ICC:1:10-1:100ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | PDXK |
| Gene ID | 8566 |
| Uniprot ID | PDXK_HUMAN |
| Immunogen Region | 1-312 |
| Immunogen Sequence | MEEECRVLSIQSHVIRGYVG NRAATFPLQVLGFEIDAVNS VQFSNHTGYAHWKGQVLNSD ELQELYEGLRLNNMNKYDYV LTGYTRDKSFLAMVVDIVQE LKQQNPRLVYVCDPVLGDKW DGEGSMYVPEDLLPVYKEKV VPLADIITPNQFEAELLSGR KIHSQEEALRVMDMLHSMGP DTVVITSSDLPSPQGSNYLI VLGSQRRRNPAGSVVMERIR MDIRKVDAVFVGTGDLFAA |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 1-312 of human PDXK (NP_003672.1). |
Additional Info
| Tissue Specificity | Ubiquitous. Highly expressed in testis. Isoform 3: In adult testis and spermatozoa. |
| Function | Catalyzes the phosphorylation of the dietary vitamin B6 vitamers pyridoxal (PL), pyridoxine (PN) and pyridoxamine (PM) to form pyridoxal 5'-phosphate (PLP), pyridoxine 5'-phosphate (PNP) and pyridoxamine 5'-phosphate (PMP), respectively (Probable). PLP is the active form of vitamin B6, and acts as a cofactor for over 140 different enzymatic reactions. |
| Protein Name | Pyridoxal KinasePyridoxine Kinase |
| Database Links | Reactome: R-HSA-6798695Reactome: R-HSA-964975 |
| Cellular Localisation | CytoplasmCytosol |
| Alternative Antibody Names | Anti-Pyridoxal Kinase antibodyAnti-Pyridoxine Kinase antibodyAnti-PDXK antibodyAnti-C21orf124 antibodyAnti-C21orf97 antibodyAnti-PKH antibodyAnti-PNK antibodyAnti-PRED79 antibody |
Information sourced from Uniprot.org