Anti-PDXK antibody (1-312) [S5014RM] (STJ11105014)
SPECIFICATIONS
ClonalityMonoclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit monoclonal Pyridoxal Kinase (1-312) antibody for use in WB and ELISA in human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | S5014RM |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:1000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.05% Proclin300, 0.05% BSA, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | PDXK |
| Gene ID | 8566 |
| Uniprot ID | PDXK_HUMAN |
| Immunogen Region | 1-312 |
| Immunogen Sequence | MEEECRVLSIQSHVIRGYVG NRAATFPLQVLGFEIDAVNS VQFSNHTGYAHWKGQVLNSD ELQELYEGLRLNNMNKYDYV LTGYTRDKSFLAMVVDIVQE LKQQNPRLVYVCDPVLGDKW DGEGSMYVPEDLLPVYKEKV VPLADIITPNQFEAELLSGR KIHSQEEALRVMDMLHSMGP DTVVITSSDLPSPQGSNYLI VLGSQRRRNPAGSVVMERIR MDIRKVDAVFVGTGDLFAA |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 1-312 of human PDXK (NP_003672.1). |
Additional Info
| Tissue Specificity | Ubiquitous. Highly expressed in testis. Isoform 3: In adult testis and spermatozoa. |
| Function | Catalyzes the phosphorylation of the dietary vitamin B6 vitamers pyridoxal (PL), pyridoxine (PN) and pyridoxamine (PM) to form pyridoxal 5'-phosphate (PLP), pyridoxine 5'-phosphate (PNP) and pyridoxamine 5'-phosphate (PMP), respectively (Probable). PLP is the active form of vitamin B6, and acts as a cofactor for over 140 different enzymatic reactions. |
| Protein Name | Pyridoxal KinasePyridoxine Kinase |
| Database Links | Reactome: R-HSA-6798695Reactome: R-HSA-964975 |
| Cellular Localisation | CytoplasmCytosol |
| Alternative Antibody Names | Anti-Pyridoxal Kinase antibodyAnti-Pyridoxine Kinase antibodyAnti-PDXK antibodyAnti-C21orf124 antibodyAnti-C21orf97 antibodyAnti-PKH antibodyAnti-PNK antibodyAnti-PRED79 antibody |
Information sourced from Uniprot.org