Anti-PDS5B antibody (90-170 aa) (STJ190546)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from the human protein at the amino acid range 90-170
General Information
| Short Description | Rabbit polyclonal anti-Sister chromatid cohesion protein PDS5 homolog B (90-170 aa) for use in WB and ELISA in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-2000ELISA 1:5000-20000 |
| Formulation | Liquid in PBS containing 50% Glycerol and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | PDS5B |
| Gene ID | 23047 |
| Uniprot ID | PDS5B_HUMAN |
| Immunogen | Synthesized peptide derived from the human protein at the amino acid range 90-170 |
| Immunogen Region | 90-170 aa |
| Specificity | PDS5B Polyclonal Antibody detects endogenous levels of protein. |
Additional Info
| Function | Regulator of sister chromatid cohesion in mitosis which may stabilize cohesin complex association with chromatin. May couple sister chromatid cohesion during mitosis to DNA replication. Cohesion ensures that chromosome partitioning is accurate in both meiotic and mitotic cells and plays an important role in DNA repair. Plays a role in androgen-induced proliferative arrest in prostate cells. |
| Protein Name | Sister Chromatid Cohesion Protein Pds5 Homolog BAndrogen-Induced Proliferation InhibitorAndrogen-Induced Prostate Proliferative Shutoff-Associated Protein As3 |
| Database Links | Reactome: R-HSA-2467813Reactome: R-HSA-2468052Reactome: R-HSA-2470946Reactome: R-HSA-2500257 |
| Cellular Localisation | Nucleus |
| Alternative Antibody Names | Anti-Sister Chromatid Cohesion Protein Pds5 Homolog B antibodyAnti-Androgen-Induced Proliferation Inhibitor antibodyAnti-Androgen-Induced Prostate Proliferative Shutoff-Associated Protein As3 antibodyAnti-PDS5B antibodyAnti-APRIN antibodyAnti-AS3 antibodyAnti-KIAA0979 antibody |
Information sourced from Uniprot.org