Anti-PDP1 antibody (72-260) (STJ116756)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal PDP1 (72-260) antibody for use in WB, IF, ICC and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IF/ICC/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:2000IF/ICC:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | PDP1 |
| Gene ID | 54704 |
| Uniprot ID | PDP1_HUMAN |
| Immunogen Region | 72-260 |
| Immunogen Sequence | ASTPQKFYLTPPQVNSILKA NEYSFKVPEFDGKNVSSILG FDSNQLPANAPIEDRRSAAT CLQTRGMLLGVFDGHAGCAC SQAVSERLFYYIAVSLLPHE TLLEIENAVESGRALLPILQ WHKHPNDYFSKEASKLYFNS LRTYWQELIDLNTGESTDID VKEALINAFKRLDNDISLEA QVGDPNSFL |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 72-260 of human PDP1 (NP_060914.2). |
Additional Info
| Function | Mitochondrial enzyme that catalyzes the dephosphorylation and concomitant reactivation of the alpha subunit of the E1 component of the pyruvate dehydrogenase complex (PDC), thereby stimulating the conversion of pyruvate into acetyl-CoA. |
| Protein Name | Pyruvate Dehydrogenase Acetyl-Transferring-Phosphatase 1 - MitochondrialPdp 1Protein Phosphatase 2cPyruvate Dehydrogenase Phosphatase Catalytic Subunit 1Pdpc 1 |
| Database Links | Reactome: R-HSA-204174 |
| Cellular Localisation | Mitochondrion |
| Alternative Antibody Names | Anti-Pyruvate Dehydrogenase Acetyl-Transferring-Phosphatase 1 - Mitochondrial antibodyAnti-Pdp 1 antibodyAnti-Protein Phosphatase 2c antibodyAnti-Pyruvate Dehydrogenase Phosphatase Catalytic Subunit 1 antibodyAnti-Pdpc 1 antibodyAnti-PDP1 antibodyAnti-PDP antibodyAnti-PPM2C antibody |
Information sourced from Uniprot.org