Anti-PDLIM7 antibody [R05-5A1] (STJA0034702)
SPECIFICATIONS
ClonalityMonoclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenRecombinant protein of human PDLIM7
General Information
| Short Description | Rabbit monoclonal anti-PDLIM7 for use in WB in Human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB |
| Host | Rabbit |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | R05-5A1 |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 0.3 mg/mL |
| Purification | Affinity Purified |
| Dilution Range | WB 1:500-1:1000 |
| Formulation | 50mM Tris-Glycine (pH 7.4) , 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA |
| Storage Instruction | Store at 4°C short term. Aliquot and store at-20°C long term. Avoid freeze/thaw cycles. |
Target Information
| Gene Symbol | PDLIM7 |
| Gene ID | 9260 |
| Uniprot ID | PDLI7_HUMAN |
| Immunogen | Recombinant protein of human PDLIM7 |
Additional Info
| Tissue Specificity | Isoform 1 and isoform 2 are expressed ubiquitously, however, isoform 2 predominates in skeletal muscle, isoform 1 is more abundant in lung, spleen, leukocytes and fetal liver. |
| Function | May function as a scaffold on which the coordinated assembly of proteins can occur. May play a role as an adapter that, via its PDZ domain, localizes LIM-binding proteins to actin filaments of both skeletal muscle and nonmuscle tissues. Involved in both of the two fundamental mechanisms of bone formation, direct bone formation (e.g. embryonic flat bones mandible and cranium), and endochondral bone formation (e.g. embryonic long bone development). Plays a role during fracture repair. Involved in BMP6 signaling pathway. |
| Protein Name | Pdz And Lim Domain Protein 7Lim Mineralization ProteinLmpProtein Enigma |
| Database Links | Reactome: R-HSA-8853659 |
| Cellular Localisation | CytoplasmCytoskeletonColocalizes With Ret To The Cell Periphery And In Some Cytoskeletal ComponentsColocalizes With Tpm2 Near The Z Line In MuscleColocalizes With Tbx4 And Tbx5 To Actin Filaments |
| Alternative Antibody Names | Anti-Pdz And Lim Domain Protein 7 antibodyAnti-Lim Mineralization Protein antibodyAnti-Lmp antibodyAnti-Protein Enigma antibodyAnti-PDLIM7 antibodyAnti-ENIGMA antibody |
Information sourced from Uniprot.org