Anti-PDIA2 antibody (326-525) (STJ114937)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal PDIA2 (326-525) antibody for use in WB, IF, ICC and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IF/ICC/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:2000IF/ICC:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | PDIA2 |
| Gene ID | 64714 |
| Uniprot ID | PDIA2_HUMAN |
| Immunogen Region | 326-525 |
| Immunogen Sequence | FGLKAEAAPTLRLVNLETTK KYAPVDGGPVTAASITAFCH AVLNGQVKPYLLSQEIPPDW DQRPVKTLVGKNFEQVAFDE TKNVFVKFYAPWCTHCKEMA PAWEALAEKYQDHEDIIIAE LDATANELDAFAVHGFPTLK YFPAGPGRKVIEYKSTRDLE TFSKFLDNGGVLPTEEPPEE PAAPFPEPPANSTMGSKEEL |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 326-525 of human PDIA2 (NP_006840.2). |
Additional Info
| Tissue Specificity | Highly expressed in pancreas (at protein level). |
| Post Translational Modifications | The disulfide-linked homodimer exhibits an enhanced chaperone activity. Glycosylated. |
| Function | Acts as an intracellular estrogen-binding protein. May be involved in modulating cellular levels and biological functions of estrogens in the pancreas. May act as a chaperone that inhibits aggregation of misfolded proteins. |
| Protein Name | Protein Disulfide-Isomerase A2Pancreas-Specific Protein Disulfide IsomerasePdip |
| Database Links | Reactome: R-HSA-9925561 |
| Cellular Localisation | Endoplasmic Reticulum Lumen |
| Alternative Antibody Names | Anti-Protein Disulfide-Isomerase A2 antibodyAnti-Pancreas-Specific Protein Disulfide Isomerase antibodyAnti-Pdip antibodyAnti-PDIA2 antibodyAnti-PDIP antibody |
Information sourced from Uniprot.org