| Post Translational Modifications | Delipoylated at Lys-97 by SIRT4, delipoylation decreases the PHD complex activity. |
| Function | Required for anchoring dihydrolipoamide dehydrogenase (E3) to the dihydrolipoamide transacetylase (E2) core of the pyruvate dehydrogenase complexes of eukaryotes. This specific binding is essential for a functional PDH complex. |
| Protein Name | Pyruvate Dehydrogenase Protein X Component - MitochondrialDihydrolipoamide Dehydrogenase-Binding Protein Of Pyruvate Dehydrogenase ComplexE3-Binding ProteinE3bpLipoyl-Containing Pyruvate Dehydrogenase Complex Component XProx |
| Database Links | Reactome: R-HSA-204174Reactome: R-HSA-5362517Reactome: R-HSA-9861559 |
| Cellular Localisation | Mitochondrion Matrix |
| Alternative Antibody Names | Anti-Pyruvate Dehydrogenase Protein X Component - Mitochondrial antibodyAnti-Dihydrolipoamide Dehydrogenase-Binding Protein Of Pyruvate Dehydrogenase Complex antibodyAnti-E3-Binding Protein antibodyAnti-E3bp antibodyAnti-Lipoyl-Containing Pyruvate Dehydrogenase Complex Component X antibodyAnti-Prox antibodyAnti-PDHX antibodyAnti-PDX1 antibody |
Information sourced from Uniprot.org
