Anti-PDHB antibody (1-300) (STJ29023)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal PDHB (1-300) antibody for use in WB and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | PDHB |
| Gene ID | 5162 |
| Uniprot ID | ODPB_HUMAN |
| Immunogen Region | 1-300 |
| Immunogen Sequence | MAAVSGLVRRPLREVSGLLK RRFHWTAPAALQVTVRDAIN QGMDEELERDEKVFLLGEEV AQYDGAYKVSRGLWKKYGDK RIIDTPISEMGFAGIAVGAA MAGLRPICEFMTFNFSMQAI DQVINSAAKTYYMSGGLQPV PIVFRGPNGASAGVAAQHSQ CFAAWYGHCPGLKVVSPWNS EDAKGLIKSAIRDNNPVVVL ENELMYGVPFEFPPEAQSKD FLIPIGKAKIERQGTHITV |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 1-300 of human PDHB (NP_000916.2). |
Additional Info
| Function | The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2), and thereby links the glycolytic pathway to the tricarboxylic cycle. |
| Protein Name | Pyruvate Dehydrogenase E1 Component Subunit Beta - MitochondrialPdhe1-B |
| Database Links | Reactome: R-HSA-204174Reactome: R-HSA-5362517Reactome: R-HSA-9837999Reactome: R-HSA-9861559 |
| Cellular Localisation | Mitochondrion Matrix |
| Alternative Antibody Names | Anti-Pyruvate Dehydrogenase E1 Component Subunit Beta - Mitochondrial antibodyAnti-Pdhe1-B antibodyAnti-PDHB antibodyAnti-PHE1B antibody |
Information sourced from Uniprot.org