• Western blot analysis of lysate from L929 cells, using PDGFD Antibody.
  • Immunohistochemical analysis of paraffin-embedded human-mammary-cancer, antibody was diluted at 1:100
  • Immunohistochemical analysis of paraffin-embedded human-lung-cancer, antibody was diluted at 1:100
  • Western blot analysis of L929 cells using PDGF-D Polyclonal Antibody.. Secondary antibody was diluted at 1:20000

Anti-PDGFD antibody (311-360 aa) (STJ96664)

SKU:
STJ96664

£46.00 - £226.00
Current Stock:
Host: Rabbit
Applications: WB/IHC/IF/ELISA
Reactivity: Human/Rat/Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-Platelet-derived growth factor D (311-360 aa) is suitable for use in Western Blot, Immunohistochemistry, Immunofluorescence and ELISA research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/mL
Dilution Range: WB 1:500-1:2000
IHC-P 1:100-1:300
ELISA 1:20000
IF 1:50-200
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: PDGFD
Gene ID: 80310
Uniprot ID: PDGFD_HUMAN
Immunogen Region: 311-360 aa
Specificity: PDGF-D Polyclonal Antibody detects endogenous levels of PDGF-D protein.
Immunogen: The antiserum was produced against synthesized peptide derived from the C-terminal region of human PDGFD at the amino acid range 311-360
Post Translational Modifications Activated by proteolytic cleavage. Proteolytic removal of the N-terminal CUB domain releasing the core domain is necessary for unmasking the receptor-binding epitopes of the core domain. Cleavage after Arg-247 or Arg-249 by urokinase plasminogen activator gives rise to the active form.
Function Growth factor that plays an essential role in the regulation of embryonic development, cell proliferation, cell migration, survival and chemotaxis. Potent mitogen for cells of mesenchymal origin. Plays an important role in wound healing. Induces macrophage recruitment, increased interstitial pressure, and blood vessel maturation during angiogenesis. Can initiate events that lead to a mesangial proliferative glomerulonephritis, including influx of monocytes and macrophages and production of extracellular matrix.
Protein Name Platelet-Derived Growth Factor D
Pdgf-D
Iris-Expressed Growth Factor
Spinal Cord-Derived Growth Factor B
Scdgf-B Cleaved Into - Platelet-Derived Growth Factor D - Latent Form
Pdgfd Latent Form - Platelet-Derived Growth Factor D - Receptor-Binding Form
Pdgfd Receptor-Binding Form
Database Links Reactome: R-HSA-186797
Cellular Localisation Secreted
Released By Platelets Upon Wounding
Alternative Antibody Names Anti-Platelet-Derived Growth Factor D antibody
Anti-Pdgf-D antibody
Anti-Iris-Expressed Growth Factor antibody
Anti-Spinal Cord-Derived Growth Factor B antibody
Anti-Scdgf-B Cleaved Into - Platelet-Derived Growth Factor D - Latent Form antibody
Anti-Pdgfd Latent Form - Platelet-Derived Growth Factor D - Receptor-Binding Form antibody
Anti-Pdgfd Receptor-Binding Form antibody
Anti-PDGFD antibody
Anti-IEGF antibody
Anti-SCDGFB antibody
Anti-MSTP036 antibody
Anti-UNQ1899 antibody
Anti-PRO4345 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance