Anti-PDGFB antibody (16-65 aa) (STJ94996)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenThe antiserum was produced against synthesized peptide derived from the human PDGFB at the amino acid range 16-65
General Information
| Short Description | Rabbit polyclonal anti-Platelet-derived growth factor subunit B (16-65 aa) for use in IF, WB, IHC and ELISA in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | IF/WB/IHC/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | IF 1:50-200WB 1:500-1:2000IHC 1:100-1:300ELISA 1:10000 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | PDGFB |
| Gene ID | 5155 |
| Uniprot ID | PDGFB_HUMAN |
| Immunogen | The antiserum was produced against synthesized peptide derived from the human PDGFB at the amino acid range 16-65 |
| Immunogen Region | 16-65 aa |
| Specificity | PDGF-B Polyclonal Antibody detects endogenous levels of PDGF-B protein. |
Additional Info
| Function | Growth factor that plays an essential role in the regulation of embryonic development, cell proliferation, cell migration, survival and chemotaxis. Potent mitogen for cells of mesenchymal origin. Required for normal proliferation and recruitment of pericytes and vascular smooth muscle cells in the central nervous system, skin, lung, heart and placenta. Required for normal blood vessel development, and for normal development of kidney glomeruli. Plays an important role in wound healing. Signaling is modulated by the formation of heterodimers with PDGFA. |
| Protein Name | Platelet-Derived Growth Factor Subunit BPdgf Subunit BPdgf-2Platelet-Derived Growth Factor B ChainPlatelet-Derived Growth Factor Beta PolypeptideProto-Oncogene C-SisBecaplermin |
| Database Links | Reactome: R-HSA-114608Reactome: R-HSA-1257604Reactome: R-HSA-186763Reactome: R-HSA-186797Reactome: R-HSA-2219530Reactome: R-HSA-3000171Reactome: R-HSA-5673001Reactome: R-HSA-6811558 |
| Cellular Localisation | SecretedReleased By Platelets Upon Wounding |
| Alternative Antibody Names | Anti-Platelet-Derived Growth Factor Subunit B antibodyAnti-Pdgf Subunit B antibodyAnti-Pdgf-2 antibodyAnti-Platelet-Derived Growth Factor B Chain antibodyAnti-Platelet-Derived Growth Factor Beta Polypeptide antibodyAnti-Proto-Oncogene C-Sis antibodyAnti-Becaplermin antibodyAnti-PDGFB antibodyAnti-PDGF2 antibodyAnti-SIS antibody |
Information sourced from Uniprot.org