Anti-PDGFA antibody (21-110) (STJ119551)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal PDGFA (21-110) antibody for use in IHC-P and ELISA in human and mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | IHC-P/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | IHC-P:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | PDGFA |
| Gene ID | 5154 |
| Uniprot ID | PDGFA_HUMAN |
| Immunogen Region | 21-110 |
| Immunogen Sequence | EEAEIPREVIERLARSQIHS IRDLQRLLEIDSVGSEDSLD TSLRAHGVHATKHVPEKRPL PIRRKRSIEEAVPAVCKTRT VIYEIPRSQV |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 21-110 of human PDGFA (NP_002598.4). |
Additional Info
| Function | Growth factor that plays an essential role in the regulation of embryonic development, cell proliferation, cell migration, survival and chemotaxis. Potent mitogen for cells of mesenchymal origin. Required for normal lung alveolar septum formation during embryogenesis, normal development of the gastrointestinal tract, normal development of Leydig cells and spermatogenesis. Required for normal oligodendrocyte development and normal myelination in the spinal cord and cerebellum. Plays an important role in wound healing. Signaling is modulated by the formation of heterodimers with PDGFB. |
| Protein Name | Platelet-Derived Growth Factor Subunit APdgf Subunit APdgf-1Platelet-Derived Growth Factor A ChainPlatelet-Derived Growth Factor Alpha Polypeptide |
| Database Links | Reactome: R-HSA-114608 P04085-1Reactome: R-HSA-1257604Reactome: R-HSA-186763Reactome: R-HSA-186797Reactome: R-HSA-2219530Reactome: R-HSA-3000171Reactome: R-HSA-5673001Reactome: R-HSA-6811558Reactome: R-HSA-9818030 |
| Cellular Localisation | SecretedReleased By Platelets Upon Wounding |
| Alternative Antibody Names | Anti-Platelet-Derived Growth Factor Subunit A antibodyAnti-Pdgf Subunit A antibodyAnti-Pdgf-1 antibodyAnti-Platelet-Derived Growth Factor A Chain antibodyAnti-Platelet-Derived Growth Factor Alpha Polypeptide antibodyAnti-PDGFA antibodyAnti-PDGF1 antibody |
Information sourced from Uniprot.org