Anti-PDE6B antibody {FITC} (STJ502362)

Name: Anti-PDE6B antibody {FITC} (STJ502362)
SKU: STJ502362-100
Price: 497.5 GBP
Availability: InStock

⇓ Datasheet ⇓ SDS

SPECIFICATIONS

ClonalityPolyclonal

HostRabbit

ConjugationFITC

IsotypeIgG

ImmunogenSynthetic cyclic petide common to all PDE6 Beta variants

STJ502362-100

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Short Description	Rabbit polyclonal antibody anti-PDE6B is suitable for use in ELISA, Confocal Microscopy, Immunocytochemistry, Immunofluorescence, Immunohistochemistry and Western Blot research applications.
Applications	ELISA/CM/ICC/IF/IHC/WB
Host	Rabbit
Reactivity	Bovine/Human/Mouse/Pig/Rat
Note	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Clonality	Polyclonal
Isotype	IgG
Conjugation	FITC
Concentration	0.5 µg/µl
Purification	Affinity Purified
Dilution Range	WB: 1:500 DB: 1:10, 000 ELISA: 1:10, 000 IHC: 1:200 ICC: 1:200 IF: 1:200 CFM: 1:200
Formulation	Contains Tris, HCl/Glycine buffer pH 7.4-7.8, 30% Glycerol and 0.5% BSA, along with cryo-protective agents, Hepes, and long-term preservatives (0.02% Sodium Azide).
Storage Instruction	Store at-20°C for long term storage. Avoid freeze-thaw cycles.

Gene Symbol	PDE6B
Gene ID	5158
Uniprot ID	PDE6B_HUMAN
Immunogen	Synthetic cyclic petide common to all PDE6 Beta variants

Function	Rod-specific cGMP phosphodiesterase that catalyzes the hydrolysis of 3',5'-cyclic GMP. Necessary for the formation of a functional phosphodiesterase holoenzyme. Involved in retinal circadian rhythm photoentrainment via modulation of UVA and orange light-induced phase-shift of the retina clock. May participate in processes of transmission and amplification of the visual signal.
Protein Name	Rod Cgmp-Specific 3' -5'-Cyclic Phosphodiesterase Subunit Beta Gmp-Pde Beta
Database Links	Reactome: R-HSA-2485179 Reactome: R-HSA-2514859 Reactome: R-HSA-4086398
Cellular Localisation	Membrane Lipid-Anchor Cell Projection Cilium Photoreceptor Outer Segment
Alternative Antibody Names	Anti-Rod Cgmp-Specific 3' -5'-Cyclic Phosphodiesterase Subunit Beta antibody Anti-Gmp-Pde Beta antibody Anti-PDE6B antibody Anti-PDEB antibody

Information sourced from Uniprot.org