Anti-PDE6A antibody (656-860) (STJ110224)

Name: Anti-PDE6A antibody (656-860) (STJ110224)
SKU: STJ110224
Availability: InStock

⇓ Datasheet ⇓ SDS

SPECIFICATIONS

ClonalityPolyclonal

HostRabbit

ConjugationUnconjugated

IsotypeIgG

STJ110224

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Short Description	Rabbit polyclonal PDE6A (656-860) antibody for use in WB and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents.
Applications	WB/ELISA
Host	Rabbit
Reactivity	Human/Mouse/Rat
Note	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Clonality	Polyclonal
Isotype	IgG
Conjugation	Unconjugated
Concentration	Lot specific
Purification	Affinity purification
Dilution Range	WB:1:500-1:2000 ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements.
Formulation	PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3.
Storage Instruction	Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.

Gene Symbol	PDE6A
Gene ID	5145
Uniprot ID	PDE6A_HUMAN
Immunogen Region	656-860
Immunogen Sequence	EHAIHMMDIAIIATDLALYF KKRTMFQKIVDQSKTYESEQ EWTQYMMLEQTRKEIVMAMM MTACDLSAITKPWEVQSQVA LLVAAEFWEQGDLERTVLQQ NPIPMMDRNKADELPKLQVG FIDFVCTFVYKEFSRFHEEI TPMLDGITNNRKEWKALADE YDAKMKVQEEKKQKQQSAKS AAAGNQPGGNPSPGGATTSK SCCIQ
Specificity	Recombinant fusion protein containing a sequence corresponding to amino acids 656-860 of human PDE6A (NP_000431.2).

Function	Rod-specific cGMP phosphodiesterase that catalyzes the hydrolysis of 3',5'-cyclic GMP. This protein participates in processes of transmission and amplification of the visual signal.
Protein Name	Rod Cgmp-Specific 3' -5'-Cyclic Phosphodiesterase Subunit Alpha Gmp-Pde Alpha Pde V-B1
Database Links	Reactome: R-HSA-2485179 Reactome: R-HSA-2514859 Reactome: R-HSA-4086398
Cellular Localisation	Cell Membrane Lipid-Anchor Cytoplasmic Side Cell Projection Cilium Photoreceptor Outer Segment
Alternative Antibody Names	Anti-Rod Cgmp-Specific 3' -5'-Cyclic Phosphodiesterase Subunit Alpha antibody Anti-Gmp-Pde Alpha antibody Anti-Pde V-B1 antibody Anti-PDE6A antibody Anti-PDEA antibody

Information sourced from Uniprot.org