Anti-PDE4D7 antibody (STJ502340)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthetic peptideΒ corresponding to unique amino acid sequence on PDE4D7 variant.
General Information
| Short Description | Rabbit polyclonal antibody anti-PDE4D7 is suitable for use in ELISA, Immunoprecipitation and Western Blot research applications. |
| Applications | ELISA/IP/WB |
| Host | Rabbit |
| Reactivity | Chicken/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 0.2 Β΅g/Β΅l |
| Purification | Affinity Purified |
| Dilution Range | WB: 1:500DB: 1:10, 000ELISA: 1:10, 000IP: 1:150 |
| Formulation | Contains Tris, HCl/Glycine buffer pH 7.4-7.8, 30% Glycerol and 0.5% BSA, along with cryo-protective agents, Hepes, and long-term preservatives (0.02% Sodium Azide). |
| Storage Instruction | Store at-20Β°C for long term storage. Avoid freeze-thaw cycles. |
Target Information
| Gene Symbol | Pde4d |
| Gene ID | 238871 |
| Uniprot ID | PDE4D_MOUSE |
| Immunogen | Synthetic peptideΒ corresponding to unique amino acid sequence on PDE4D7 variant. |
| Specificity | Does not crossDoes not cross react with other PDE family members including PDE4A, PDE4B or PDE4C. |
Additional Info
| Tissue Specificity | Expressed in brain (at protein level). Isoform 7 is detected in heart, brain, lung, kidney and testis. |
| Post Translational Modifications | Sumoylation of long isoforms by PIAS4 augments their activation by PKA phosphorylation and represses their inhibition by ERK phosphorylation. |
| Function | Hydrolyzes the second messenger cAMP, which is a key regulator of many important physiological processes. |
| Protein Name | 3' -5'-Cyclic-Amp Phosphodiesterase 4dDpde3Camp-Specific Phosphodiesterase 4d |
| Database Links | Reactome: R-MMU-180024Reactome: -MMU-418555 |
| Cellular Localisation | CytoplasmMembraneCytoskeletonMicrotubule Organizing CenterCentrosomeApical Cell MembraneColocalized With Shank2 To The Apical Membrane Of Colonic Crypt CellsFound In The Soluble FractionAssociated With MembranesAnd Associated With The Cytoskeleton And The Centrosome |
| Alternative Antibody Names | Anti-3' -5'-Cyclic-Amp Phosphodiesterase 4d antibodyAnti-Dpde3 antibodyAnti-Camp-Specific Phosphodiesterase 4d antibodyAnti-Pde4d antibody |
Information sourced from Uniprot.org