| Host: |
Rabbit |
| Applications: |
CM/ELISA/ICC/IF/IHC/IP/WB |
| Reactivity: |
Human/Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-PDE4B (C-Term) is suitable for use in Confocal Microscopy, ELISA, Immunocytochemistry, Immunofluorescence, Immunohistochemistry, Immunoprecipitation and Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Biotin |
| Isotype: |
IgG |
| Purification: |
Affinity Purified |
| Concentration: |
0.57 µg/µl |
| Dilution Range: |
WB: 1:500DB: 1:10, 000ELISA: 1:10, 000IP: 1:150 |
| Storage Instruction: |
Store at-20°C for long term storage. Avoid freeze-thaw cycles. |
| Gene Symbol: |
PDE4B |
| Gene ID: |
5142 |
| Uniprot ID: |
PDE4B_HUMAN |
| Immunogen Region: |
C-Term |
| Specificity: |
Does not cross react with PDE4A, PDE4B, PDE4D6, PDE4D7, PDE4D8, PDE4D9, OR PDE4C. |
| Immunogen: |
C-terminal cyclic peptide unique to all PDED subtypes variants. |
| Tissue Specificity | Expressed in brain, heart, lung and skeletal muscle. Expressed in white blood cells. Isoform PDE4B5: Brain-specific isoform. |
| Function | Hydrolyzes the second messenger cAMP, which is a key regulator of many important physiological processes. May be involved in mediating central nervous system effects of therapeutic agents ranging from antidepressants to antiasthmatic and anti-inflammatory agents. |
| Protein Name | Camp-Specific 3' -5'-Cyclic Phosphodiesterase 4bDpde4Pde32 |
| Database Links | Reactome: R-HSA-180024 Q07343-3 |
| Cellular Localisation | Isoform Pde4b5: CytoplasmCell Membrane |
| Alternative Antibody Names | Anti-Camp-Specific 3' -5'-Cyclic Phosphodiesterase 4b antibodyAnti-Dpde4 antibodyAnti-Pde32 antibodyAnti-PDE4B antibodyAnti-DPDE4 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
