Anti-PDE4B antibody (1-50) {FITC} (STJ502310)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationFITC
IsotypeIgG
ImmunogenSynthetic peptide taken within amino acid region 1-50 on human PDE4B2 protein.
General Information
| Short Description | Rabbit polyclonal antibody anti-PDE4B (1-50) is suitable for use in ELISA, Immunoprecipitation and Western Blot research applications. |
| Applications | ELISA/IP/WB |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | FITC |
| Concentration | 0.5 ยตg/ยตl |
| Purification | Affinity Purified |
| Dilution Range | WB: 1:750DB: 1:10, 000ELISA: 1:10, 000IP: 1:200 |
| Formulation | Contains Tris, HCl/Glycine buffer pH 7.4-7.8, 30% Glycerol and 0.5% BSA, along with cryo-protective agents, Hepes, and long-term preservatives (0.02% Sodium Azide). |
| Storage Instruction | Store at-20ยฐC for long term storage. Avoid freeze-thaw cycles. |
Target Information
| Gene Symbol | PDE4B |
| Gene ID | 5142 |
| Uniprot ID | PDE4B_HUMAN |
| Immunogen | Synthetic peptide taken within amino acid region 1-50 on human PDE4B2 protein. |
| Immunogen Region | 1-50 |
| Specificity | This antibody will detect only PDE4B2. It will not label other PDE family members. |
Additional Info
| Tissue Specificity | Expressed in brain, heart, lung and skeletal muscle. Expressed in white blood cells. Isoform PDE4B5: Brain-specific isoform. |
| Function | Hydrolyzes the second messenger cAMP, which is a key regulator of many important physiological processes. May be involved in mediating central nervous system effects of therapeutic agents ranging from antidepressants to antiasthmatic and anti-inflammatory agents. |
| Protein Name | 3' -5'-Cyclic-Amp Phosphodiesterase 4bDpde4Pde32Camp-Specific Phosphodiesterase 4b |
| Database Links | Reactome: R-HSA-180024 Q07343-3 |
| Cellular Localisation | Isoform Pde4b5: CytoplasmCell Membrane |
| Alternative Antibody Names | Anti-3' -5'-Cyclic-Amp Phosphodiesterase 4b antibodyAnti-Dpde4 antibodyAnti-Pde32 antibodyAnti-Camp-Specific Phosphodiesterase 4b antibodyAnti-PDE4B antibodyAnti-DPDE4 antibody |
Information sourced from Uniprot.org