• Western Blot analysis of Hela lysis, using primary antibody at 1:1000 dilution. Secondary antibody (STJS000791) was diluted at 1:10000

Anti-PDE2A antibody (STJ190686)

SKU:
STJ190686

$62.10 - $305.10
Current Stock:
Host: Rabbit
Applications: WB/ELISA
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-cGMP-dependent 3 NA, 5 cyclic phosphodiesterase is suitable for use in Western Blot and ELISA research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% Glycerol and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/mL
Dilution Range: WB 1:500-2000
ELISA 1:5000-20000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: PDE2A
Gene ID: 5138
Uniprot ID: PDE2A_HUMAN
Specificity: PDE2A Polyclonal Antibody detects endogenous levels of protein.
Immunogen: Synthesized peptide derived from part of the human protein
Function cGMP-activated cyclic nucleotide phosphodiesterase with a dual-specificity for the second messengers cAMP and cGMP, which are key regulators of many important physiological processes. Has a higher efficiency with cGMP compared to cAMP. Plays a role in cell growth and migration. Isoform PDE2A2: Regulates mitochondrial cAMP levels and respiration. Involved in the regulation of mitochondria morphology/dynamics and apoptotic cell death via local modulation of cAMP/PKA signaling in the mitochondrion, including the monitoring of local cAMP levels at the outer mitochondrial membrane and of PKA-dependent phosphorylation of DNM1L.
Protein Name Cgmp-Dependent 3' -5'-Cyclic Phosphodiesterase
Cyclic Gmp-Stimulated Phosphodiesterase
Cgs-Pde
Cgspde
Database Links Reactome: R-HSA-418457
Reactome: R-HSA-418555
Cellular Localisation Isoform Pde2a3: Cell Membrane
Lipid-Anchor
Isoform Pde2a2: Mitochondrion Matrix
Mitochondrion Inner Membrane
Mitochondrion Outer Membrane
Isoform Pde2a1: Cytoplasm
Isoform 5: Mitochondrion
Alternative Antibody Names Anti-Cgmp-Dependent 3' -5'-Cyclic Phosphodiesterase antibody
Anti-Cyclic Gmp-Stimulated Phosphodiesterase antibody
Anti-Cgs-Pde antibody
Anti-Cgspde antibody
Anti-PDE2A antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance