Anti-PDE1B antibody (190-536) (STJ24930)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal PDE1B (190-536) antibody for use in WB, IHC-P and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IHC-P/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:2000IHC-P:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | PDE1B |
| Gene ID | 5153 |
| Uniprot ID | PDE1B_HUMAN |
| Immunogen Region | 190-536 |
| Immunogen Sequence | RHNLISRFKIPTVFLMSFLD ALETGYGKYKNPYHNQIHAA DVTQTVHCFLLRTGMVHCLS EIELLAIIFAAAIHDYEHTG TTNSFHIQTKSECAIVYNDR SVLENHHISSVFRLMQDDEM NIFINLTKDEFVELRALVIE MVLATDMSCHFQQVKTMKTA LQQLERIDKPKALSLLLHAA DISHPTKQWLVHSRWTKALM EEFFRQGDKEAELGLPFSPL CDRTSTLVAQSQIGFIDFI |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 190-536 of human PDE1B (NP_000915.1). |
Additional Info
| Function | Cyclic nucleotide phosphodiesterase with a dual specificity for the second messengers cAMP and cGMP, which are key regulators of many important physiological processes. Has a preference for cGMP as a substrate. |
| Protein Name | Dual Specificity Calcium/Calmodulin-Dependent 3' -5'-Cyclic Nucleotide Phosphodiesterase 1bCam-Pde 1b63 Kda Cam-Pde |
| Database Links | Reactome: R-HSA-111957Reactome: R-HSA-418457Reactome: R-HSA-418555 |
| Cellular Localisation | CytoplasmCytosol |
| Alternative Antibody Names | Anti-Dual Specificity Calcium/Calmodulin-Dependent 3' -5'-Cyclic Nucleotide Phosphodiesterase 1b antibodyAnti-Cam-Pde 1b antibodyAnti-63 Kda Cam-Pde antibodyAnti-PDE1B antibodyAnti-PDES1B antibody |
Information sourced from Uniprot.org